CCL21-48H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant Human CCL21 Protein was expressed in E. coli.
Description :
CCL21 is a human chemokine that recruits normal immune cells and metastasizing tumor cells to lymph nodes through activation of the G protein-coupled receptor CCR7. Originally called SLC or exodus-2, CCL21 is expressed in high endothelial venules of lymph nodes, spleen, and Peyer's patches as well as lymphatic endothelium in peripheral tissues. CCL21 directs the migration of CCR7-expressing lymphocytes and antigen-activated dendritic cells. CCL21 contains 6 conserved cysteines, in contrast to the 4 that are more typical of CC chemokines. CCL21 induces chemotactic migration of thymocytes and activated T-cells, but not B-cells, macrophages, or neutrophils.
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