| Cat.No. : |
CCL21-48H
Optional Service: Optional requirements on this protein
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| Product Overview : |
Recombinant Human CCL21 Protein was expressed in E. coli. |
| Description : |
CCL21 is a human chemokine that recruits normal immune cells and metastasizing tumor cells to lymph nodes through activation of the G protein-coupled receptor CCR7. Originally called SLC or exodus-2, CCL21 is expressed in high endothelial venules of lymph nodes, spleen, and Peyer's patches as well as lymphatic endothelium in peripheral tissues. CCL21 directs the migration of CCR7-expressing lymphocytes and antigen-activated dendritic cells. CCL21 contains 6 conserved cysteines, in contrast to the 4 that are more typical of CC chemokines. CCL21 induces chemotactic migration of thymocytes and activated T-cells, but not B-cells, macrophages, or neutrophils. |
| Source : |
E. coli |
| Species : |
Human |
| Form : |
Lyophilized |
| Molecular Mass : |
12.2472 kDa |
| Protein length : |
111 amino acid |
| AA Sequence : |
SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCAD PKELWVQQLM QHLDKTPSPQ KPAQGCRKDR GASKTGKKGK GSKGCKRTER SQTPKGP |
| Endotoxin : |
Endotoxin-free <0.01 EU/ug |
| Purity : |
Purity assessed by HPLC, Mass Spectrometry, and NMR |
| Storage : |
Store at -20 to -80 centigrade for 12 months; Store at 4 centigrade for 6 months; Store at RT for 1 month. |
| tmpcolum67 : |
C-C motif chemokine ligand 21 |
| Figure : |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
