Recombinant Full Length Human CCL21 Protein, GST-tagged
Cat.No. : | CCL21-2963HF |
Product Overview : | Human CCL21 full-length ORF (NP_002980.1, 1 a.a. - 134 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 41 kDa |
Protein length : | 134 amino acids |
AA Sequence : | MAQSLALSLLILVLAFGIPRTQGSD GGAQDCCLKYSQRKIPAKVVRSYRK QEPSLGCSIPAILFLPRKRSQAELC ADPKELWVQQLMQHLDKTPSPQKPA QGCRKDRGASKTGKKGKGSKGCKRT ERSQTPKGP |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CCL21 chemokine (C-C motif) ligand 21 [ Homo sapiens ] |
Official Symbol : | CCL21 |
Synonyms : | CCL21; chemokine (C-C motif) ligand 21; SCYA21, small inducible cytokine subfamily A (Cys Cys), member 21; C-C motif chemokine 21; 6Ckine; beta chemokine exodus 2; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus 2; secondary lymphoid tissue chemokine; SLC; TCA4; exodus-2; beta chemokine exodus-2; beta-chemokine exodus-2; small-inducible cytokine A21; secondary lymphoid-tissue chemokine; small inducible cytokine subfamily A (Cys-Cys), member 21; SCYA21; MGC34555; |
Gene ID : | 6366 |
mRNA Refseq : | NM_002989 |
Protein Refseq : | NP_002980 |
MIM : | 602737 |
UniProt ID : | O00585 |
Products Types
◆ Recombinant Protein | ||
CCL21-2148H | Recombinant Human CCL21 Protein, His-tagged | +Inquiry |
CCL21-626H | Active Recombinant Human CCL21 protein(Met1-Pro134) | +Inquiry |
CCL21-513R | Recombinant Rhesus Macaque CCL21 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCL21-0625H | Active Recombinant Human CCL21 Protein | +Inquiry |
CCL21-19H | Recombinant Human CCL21 Protein | +Inquiry |
◆ Lysates | ||
CCL21-424CCL | Recombinant Cynomolgus CCL21 cell lysate | +Inquiry |
CCL21-552HCL | Recombinant Human CCL21 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewCCL21 products are reliable and stable, and are widely used in scientific research, industrial production and medical fields.
CCL21 has a long half-life and can maintain stability and reliability during the experiment.
When using CCL21 protein for experiments, it can meet specific experimental requirements and research purposes.
Q&As (6)
Ask a questionThis has a complex relationship with other genes or proteins, and can interact with other genes or proteins to participate in a variety of biochemical reactions.
It can be used as a biomarker in medical treatment to help monitor disease progression and treatment efficacy. In addition, therapeutics targeting CCL21, such as targeted therapies or modulating its expression, are also being investigated.
CCL21 deficiency or aberrant expression may be associated with some autoimmune diseases, cancer, and neurodegenerative diseases.
Abnormal levels of CCL21 may suggest autoimmune diseases, cancer, and neurodegenerative diseases, but they may also be associated with other diseases.
Studying the regulatory mechanism of CCL21 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.
Mutations in CCL21 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.
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