CCL21-123H
Optional Service: Optional requirements on this protein
Product Overview :
The extracellular domain of human CCL21 (AAH27918.1)(Ser24-Pro134) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.
Description :
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19)
Source :
CHO cell
Species :
Human
Tag :
HIgG1 Fc-tagged, mutant
Form :
Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity :
Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL).
Molecular Mass :
38KDa (monomer)
AA Sequence :
Ser24-Pro134
Endotoxin :
<0.06 eu/μg as determined by lal test.>
Purity :
>98%, by SDS-PAGE under reducing conditions.
Stability :
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.