Recombinant Human CCL21 Protein, DYKDDDDK-tagged
| Cat.No. : | CCL21-151H |
| Product Overview : | Recombinant Human chemokine (C-C motif) ligand 21 (CCL21) (NM_002989), with a DYKDDDDK tag, was expressed in human cells. |
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- Gene Information
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| Description : | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Source : | Human Cells |
| Species : | Human |
| Tag : | DYKDDDDK |
| Form : | Purified protein formulated in a sterile solution of TBS buffer, pH7.85, without any preservatives. |
| Molecular Mass : | 12.2 kDa |
| Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Purity : | >90% by SDS-PAGE gel and Coomassie Blue staining |
| Applications : | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies. |
| Gene Name : | CCL21 chemokine (C-C motif) ligand 21 [ Homo sapiens ] |
| Official Symbol : | CCL21 |
| Synonyms : | CCL21; chemokine (C-C motif) ligand 21; SCYA21, small inducible cytokine subfamily A (Cys Cys), member 21; C-C motif chemokine 21; 6Ckine; beta chemokine exodus 2; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus 2; secondary lymphoid tissue chemokine; SLC; TCA4; exodus-2; beta chemokine exodus-2; beta-chemokine exodus-2; small-inducible cytokine A21; secondary lymphoid-tissue chemokine; small inducible cytokine subfamily A (Cys-Cys), member 21; SCYA21; MGC34555; |
| Gene ID : | 6366 |
| mRNA Refseq : | NM_002989 |
| Protein Refseq : | NP_002980 |
| MIM : | 602737 |
| UniProt ID : | O00585 |
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| ◆ Recombinant Protein | ||
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| ◆ Lysates | ||
| CCL21-552HCL | Recombinant Human CCL21 cell lysate | +Inquiry |
| CCL21-424CCL | Recombinant Cynomolgus CCL21 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThis has a complex relationship with other genes or proteins, and can interact with other genes or proteins to participate in a variety of biochemical reactions.
It can be used as a biomarker in medical treatment to help monitor disease progression and treatment efficacy. In addition, therapeutics targeting CCL21, such as targeted therapies or modulating its expression, are also being investigated.
CCL21 deficiency or aberrant expression may be associated with some autoimmune diseases, cancer, and neurodegenerative diseases.
Abnormal levels of CCL21 may suggest autoimmune diseases, cancer, and neurodegenerative diseases, but they may also be associated with other diseases.
Studying the regulatory mechanism of CCL21 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.
Mutations in CCL21 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.
Customer Reviews (3)
Write a reviewCCL21 products are reliable and stable, and are widely used in scientific research, industrial production and medical fields. -
CCL21 has a long half-life and can maintain stability and reliability during the experiment. -
When using CCL21 protein for experiments, it can meet specific experimental requirements and research purposes. -
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