Recombinant Rat Ccl21 protein, His & GST-tagged

• Cat.No.: Ccl21-7139R
• Product Overview: Recombinant Rat Ccl21 aa. (Leu5~Ser132) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Rat
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: 44kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Leu5~Ser132
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >92%
• Characteristic: The isoelectric point is 8.8.
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; Reporter Assays; Purification; Amine Reactive Labeling.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200ug/mL
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: Ccl21 C-C motif chemokine ligand 21 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Ccl21
• Synonyms: Ccl21; C-C motif chemokine ligand 21; Ccl21b; C-C motif chemokine 21; chemokine (C-C motif) ligand 21; chemokine (C-C motif) ligand 21b (serine); small inducible cytokine A21
• Gene ID: 298006
• mRNA Refseq: NM_001008513.1
• Protein Refseq: NP_001008513.1
• UniProt ID: Q5RJN3

Reviews

11/21/2022

CCL21 products are reliable and stable, and are widely used in scientific research, industrial production and medical fields.

04/10/2022

CCL21 has a long half-life and can maintain stability and reliability during the experiment.

06/28/2021

When using CCL21 protein for experiments, it can meet specific experimental requirements and research purposes.

Q&As

Does CCL21 have relationships with other genes or proteins?

This has a complex relationship with other genes or proteins, and can interact with other genes or proteins to participate in a variety of biochemical reactions.

What are the applications of CCL21 in medical treatment?

It can be used as a biomarker in medical treatment to help monitor disease progression and treatment efficacy. In addition, therapeutics targeting CCL21, such as targeted therapies or modulating its expression, are also being investigated.

What diseases can CCL21 deficiency or aberrant expression cause?

CCL21 deficiency or aberrant expression may be associated with some autoimmune diseases, cancer, and neurodegenerative diseases.

Might abnormal CCL21 levels be indicative of disease?

Abnormal levels of CCL21 may suggest autoimmune diseases, cancer, and neurodegenerative diseases, but they may also be associated with other diseases.

How to study the regulatory mechanism of CCL21?

Studying the regulatory mechanism of CCL21 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

How are mutations in CCL21 detected and analyzed?

Mutations in CCL21 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.