Active Recombinant Human CCL21

Cat.No. : CCL21-522H
Product Overview : Recombinant Human CCL21 (Accession # NP_002980 (6Ckine) & P78423 (Fractalkine Mucin-like Stalk)), fused with , was produced in Mouse myeloma cell line, NS0-derived.
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Source : Mammalian cells
Species : Human
Predicted N Terminal : Ser24
Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity : Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL).The ED50 for this effect is typically 0.5 - 1.5 µg/mL.Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR7.The ED50 for this effect is typically 25 - 100 ng/mL.
Molecular Mass : Recombinant Human CCL21 has a calculated MW of 38.3 kDa. In SDS-PAGE migrates as 95-105 kDa, reducing conditions.
Purity : >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : CCL21 chemokine (C-C motif) ligand 21 [ Homo sapiens ]
Official Symbol : CCL21
Synonyms : CCL21; chemokine (C-C motif) ligand 21; SCYA21, small inducible cytokine subfamily A (Cys Cys), member 21; C-C motif chemokine 21; 6Ckine; beta chemokine exodus 2; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus 2; secondary lymphoid tissue chemokine; SLC; TCA4; exodus-2; beta chemokine exodus-2; beta-chemokine exodus-2; small-inducible cytokine A21; secondary lymphoid-tissue chemokine; small inducible cytokine subfamily A (Cys-Cys), member 21; SCYA21; MGC34555;
Gene ID : 6366
mRNA Refseq : NM_002989
Protein Refseq : NP_002980
MIM : 602737
UniProt ID : O00585
Chromosome Location : 9p13

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does CCL21 have relationships with other genes or proteins? 02/18/2022

This has a complex relationship with other genes or proteins, and can interact with other genes or proteins to participate in a variety of biochemical reactions.

What are the applications of CCL21 in medical treatment? 02/27/2021

It can be used as a biomarker in medical treatment to help monitor disease progression and treatment efficacy. In addition, therapeutics targeting CCL21, such as targeted therapies or modulating its expression, are also being investigated.

What diseases can CCL21 deficiency or aberrant expression cause? 02/02/2021

CCL21 deficiency or aberrant expression may be associated with some autoimmune diseases, cancer, and neurodegenerative diseases.

Might abnormal CCL21 levels be indicative of disease? 12/26/2020

Abnormal levels of CCL21 may suggest autoimmune diseases, cancer, and neurodegenerative diseases, but they may also be associated with other diseases.

How to study the regulatory mechanism of CCL21? 10/01/2020

Studying the regulatory mechanism of CCL21 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

How are mutations in CCL21 detected and analyzed? 03/06/2020

Mutations in CCL21 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

Customer Reviews (3)

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Reviews
11/21/2022

    CCL21 products are reliable and stable, and are widely used in scientific research, industrial production and medical fields.

    04/10/2022

      CCL21 has a long half-life and can maintain stability and reliability during the experiment.

      06/28/2021

        When using CCL21 protein for experiments, it can meet specific experimental requirements and research purposes.

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