Cd27

  • Official Full Name

    CD27 molecule

  • Overview

    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
  • Synonyms

    CD27; CD27 molecule; T14; S152; Tp55; TNFRSF7; S152. LPFS2; CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • GMP Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Cynomolgus/Rhesus macaque
  • Homo sapiens (Human)
  • Human
  • Monkey
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rhesus Macaque
  • Rhesus monkey
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian cells
  • Rabbit
  • Wheat Germ
  • Avi|Fc
  • C
  • Fc
  • hFc
  • His
  • rFc
  • DDK|His
  • Fc Chimera
  • Fc|His
  • Flag
  • hIgG
  • His (Fc)
  • Avi
  • His|Fc
  • HlgG1 Fc
  • human|IgG1|Fc
  • mFc
  • MlgG2a Fc
  • Mouse|IgG2a|Fc
  • Myc
  • DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD27-564H Active Recombinant Human CD27, Fc-tagged, Biotinylated Human Cell Fc
Human CD27-001H Active Recombinant Human CD27, MIgG2a Fc-tagged CHO Fc
Human CD27-57H Active Recombinant Human CD27 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
Human CD27-141H Active Recombinant Human CD27, Fc-tagged CHO Fc
Human CD27-003H Active Recombinant Human CD27, HIgG1 Fc-tagged CHO Fc
Human CD27-180H Recombinant Human CD27 protein, hFc-tagged HEK293 hFc
Human CD27-180HAF555 Active Recombinant Human CD27 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Human CD27-180HAF488 Active Recombinant Human CD27 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Human CD27-180HAF647 Active Recombinant Human CD27 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Human CD27-3228H Active Recombinant Human CD27 protein(Met1-Ile192), rFc-tagged HEK293 C-rFc
Human CD27-180HF Active Recombinant Human CD27 Protein, Fc-tagged, FITC conjugated HEK293 Fc
Human CD27-1345H Acitve Recombinant Human CD27 protein(Met1-Ile192), His-tagged Insect Cells C-His
Human CD27-26925TH Recombinant Human CD27 Wheat Germ N/A
Human CD27-556H Recombinant Human CD27, His tagged Insect Cell Fc
Human CD27-887H Recombinant Human CD27 Protein, DDK/His-tagged HEK293 DDK/His
Human CD27-572H Recombinant Human CD27 protein, His-tagged E.coli His
Human CD27-638H Recombinant Human CD27, Fc-His tagged Human Cell Fc/His
Human CD27-888H Recombinant Human CD27 Protein, Fc/His-tagged HEK293 Fc/His
Human CD27-1592H Recombinant Human CD27 Molecule, Fc-His Mammalian cells Fc/His
Human CD27-56H Recombinant Human CD27 Molecule, Fc-Tagged Human Cell Fc
Human CD27-7139H Recombinant Human CD27 Molecule, His-tagged E.coli His
Human CD27-001HCL Recombinant Human CD27 cell lysate Insect Cell N/A
Human CD27-1383HCL Recombinant Human CD27 cell lysate Human Cell N/A
Human CD27-6271H Recombinant Human CD27 protein, His-tagged HEK293 His
Human CD27-1079H Recombinant Human CD27 protein, Fc-tagged HEK293 human/IgG1/Fc
Human CD27-324H Active Recombinant Human CD27 protein, His-tagged, Biotinylated Insect Cells His
Human CAB11495RH Rabbit Anti-Human CD27 Molecule Monoclonal Antibody, FITC-conjugated Rabbit N/A
Human CD27-2955H Active Recombinant Human CD27 protein, mFc-tagged HEK293 mFc
Human CD27-1079HA Active Recombinant Human CD27 protein, Fc-tagged, APC-labeled HEK293 Fc
Human CD27-079HG Active GMP Recombinant Human CD27 protein, Fc-tagged HEK293 Fc
Human CD27-497H Recombinant Human CD27 Protein (Ala20-Arg191), C-hFc-tagged HEK293 C-hFc
Human CD27-622H Recombinant Human CD27 Protein, Fc-tagged HEK293 Fc
Human CD27-1079HP Recombinant Human CD27 protein, Fc-tagged, R-PE-labeled HEK293 Fc
Human CAB11497RH Rabbit Anti-Human CD27 Molecule Monoclonal Antibody Rabbit N/A
Human CD27-336H Recombinant Human CD27 protein, His-tagged HEK293 His
Human CD27-2953H Active Recombinant Human CD27 protein, His-tagged HEK293 His
Human CD27-6351H Recombinant Human CD27 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CD27-638HAF647 Recombinant Human CD27 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His
Human CD27-337H Recombinant Human CD27 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
Human CD27-638HAF488 Recombinant Human CD27 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His
Human CD27-54HF Recombinant Full Length Human CD27 Protein In Vitro Cell Free System
Human CD27-1418HFL Recombinant Full Length Human CD27 Protein, C-Flag-tagged Mammalian cells Flag
Human CD27-152H Recombinant Human CD27 Protein, His-tagged Human Cells His
Human CD27-556HAF555 Recombinant Human CD27 Protein, His-tagged, Alexa Fluor 555 conjugated Insect Cell His
Human CD27-183H Recombinant Human CD27 Protein, C-His-tagged E.coli C-His
Human CD27-223H-B Recombinant Human CD27 Protein Pre-coupled Magnetic Beads HEK293
Human CD27-06H Active Recombinant Human CD27 Protein, hIgG/His-tagged HEK293 hIgG/His
Human CD27-556HAF647 Recombinant Human CD27 Protein, His-tagged, Alexa Fluor 647 conjugated Insect Cell His
Human CD27-223H Recombinant Human CD27 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD27-5330H Recombinant Human CD27 Protein (Met1-Ile192), C-Fc tagged Mammalian cells C-Fc
Human CD27-638HAF555 Recombinant Human CD27 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His
Human CD27-556HF Recombinant Human CD27 Protein, His-tagged, FITC conjugated Insect Cell His
Human CD27-0929H Recombinant Human CD27 Protein (Thr21-Ile192), N-His tagged E.coli N-His
Human CD27-638HF Recombinant Human CD27 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His
Human CD27-5329H Recombinant Human CD27 Protein (Met1-Ile192), C-His tagged Mammalian cells C-His
Human CD27-556HAF488 Recombinant Human CD27 Protein, His-tagged, Alexa Fluor 488 conjugated Insect Cell His
Mouse Cd27-840M Active Recombinant Mouse Cd27 Protein, His & Fc-tagged HEK293 His/Fc
Mouse Cd27-840MF Active Recombinant Mouse Cd27 Protein, His/Fc-tagged, FITC conjugated HEK293 His/Fc
Mouse Cd27-840MAF488 Active Recombinant Mouse Cd27 Protein, His/Fc-tagged, Alexa Fluor 488 conjugated HEK293 His/Fc
Mouse Cd27-840MAF647 Active Recombinant Mouse Cd27 Protein, His/Fc-tagged, Alexa Fluor 647 conjugated HEK293 His/Fc
Mouse Cd27-840MAF555 Active Recombinant Mouse Cd27 Protein, His/Fc-tagged, Alexa Fluor 555 conjugated HEK293 His/Fc
Mouse Cd27-3273M Active Recombinant Mouse Cd27 protein(Met1-Arg182), His-tagged HEK293 C-His
Mouse Cd27-3258M Recombinant Mouse CD27 Antigen, Fc Chimera Human Cell Fc
Mouse CD27-2415MCL Recombinant Mouse CD27 cell lysate Human Cell N/A
Mouse Cd27-3273MAF488 Recombinant Mouse Cd27 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
Mouse Cd27-3273MF Recombinant Mouse Cd27 Protein, His-tagged, FITC conjugated HEK293 His
Mouse Cd27-2058M Recombinant Mouse Cd27 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Cd27-3273MAF647 Recombinant Mouse Cd27 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
Mouse CD27-357M Recombinant Mouse CD27 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
Mouse Cd27-3273MAF555 Recombinant Mouse Cd27 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
Mouse Cd27-365M Recombinant Mouse Cd27 Protein, His&GST-tagged E.coli N-His&GST
Mouse CD27-2954M Active Recombinant Mouse CD27 protein, mFc-tagged HEK293 mFc
Rat Cd27-643R Active Recombinant Rat Cd27, Fc Chimera Mammalian cells Fc Chimera
Rat Cd27-23R Recombinant Rat Cd27 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CD27-1875R Active Recombinant Rat CD27 protein, His-tagged HEK293 His
Rat Cd27-23R-B Recombinant Rat Cd27 Protein Pre-coupled Magnetic Beads HEK293
Rat CD27-946R Recombinant Rat CD27 Protein (Met1-Arg183), HlgG1 Fc-tagged HEK293 HlgG1 Fc
Rat CD27-947R Recombinant Rat CD27 Protein (Met1-Cys181), MlgG2a Fc-tagged HEK293 MlgG2a Fc
Monkey CD27-493RAF555 Active Recombinant Monkey CD27 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Monkey CD27-493RAF488 Active Recombinant Monkey CD27 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Monkey CD27-493RAF647 Active Recombinant Monkey CD27 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Monkey CD27-493RF Active Recombinant Monkey CD27 Protein, Fc-tagged, FITC conjugated HEK293 Fc
Rhesus monkey CD27-1654R Recombinant Rhesus Monkey CD27 Protein HEK293 N/A
Cynomolgus Monkey CD27-1156CCL Recombinant Cynomolgus CD27 cell lysate Human Cell N/A
Cynomolgus/Rhesus macaque CD27-335C Recombinant Cynomolgus/Rhesus macaque CD27 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
Homo sapiens (Human) RFL31933HF Recombinant Full Length Human Cd27 Antigen(Cd27) Protein, His-Tagged E.coli expression system His
Mus musculus (Mouse) RFL20496MF Recombinant Full Length Mouse Cd27 Antigen(Cd27) Protein, His-Tagged E.coli expression system His
Rhesus Macaque CD27-493R Active Recombinant Rhesus CD27 protein, Fc-tagged HEK293 Fc
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Cd27 Related Articles
  • Cd27 Related Gene Family
  • Cd27 Related Research Area
  • Cd27 Related Signal Pathway

Cd27 involved in several pathways and played different roles in them. We selected most pathways Cd27 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL3;IL2RA;XCL1;CCL20B;PLEKHO2;IFNA21;CCR8L;IL9;TNFRSF9

Cd27 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cd27 itself. We selected most functions Cd27 had, and list some proteins which have the same functions with Cd27. You can find most of the proteins on our site.

Function Related Protein
cysteine-type endopeptidase inhibitor activity involved in apoptotic processSERPINB9;RPS6KA1;AVP;C1QL4L;CD27;BIRC3;BIRC8;BIRC2;PRDX3
protein bindingCD37;CDCP1;IL23R;TMX3;ACYP2;HOOK1;CXADR;KCNJ3;BCKDHA
transmembrane signaling receptor activityANTXR1;TLR9;LILRB5;CALCRLA;EGFR;SELE;FZD3A;Cd79a, Cd79b;IL1R1
tumor necrosis factor-activated receptor activityTNFRSF11A;TNFRSF10D;TNFRSF10B;NGFR;LTBR;TNFRSF21;TNFRSF10C;TNFRSF11B;TNFRSF4

Cd27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd27 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd27.

SIVA1; UHRF2; TRAF2

Convers, KD; Kariuki, BM; et al. Decreased CD5(-)CD19(+)CD27(+)CD43(+)CD70(-) B-Cell Subpopulation in Children with Specific Antibody Deficiency. PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY 28:27-31(2015).
Becerra, E; Scully, MA; et al. Effect of rituximab on B cell phenotype and serum B cell-activating factor levels in patients with thrombotic thrombocytopenic purpura. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 179:414-425(2015).
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