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Official Full Name CD27 molecule
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Synonyms CD27; CD27 molecule; T14; S152; Tp55; TNFRSF7; S152. LPFS2; CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7;
    • Species :
    • Cynomolgus Monkey
    • Cynomolgus/Rhesus macaque
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Source :
    • CHO
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Human Cells
    • Insect Cell
    • Mammalian cells
    • Rabbit
    • Wheat Germ
    • Tag :
    • Avi
    • Fc
    • DDK
    • His
    • Fc Chimera
    • HlgG1 Fc
    • human
    • IgG1
    • MlgG2a Fc
    • Mouse
    • IgG2a
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD27-152H Recombinant Human CD27 Protein, His-tagged Human Cells His
    Human CAB11495RH Rabbit Anti-Human CD27 Molecule Monoclonal Antibody, FITC-conjugated Rabbit N/A
    Human CAB11497RH Rabbit Anti-Human CD27 Molecule Monoclonal Antibody Rabbit N/A
    Human CD27-001H Recombinant Human CD27, MIgG2a Fc-tagged CHO Fc
    Human CD27-001HCL Recombinant Human CD27 cell lysate Insect Cell N/A
    Human CD27-003H Recombinant Human CD27, HIgG1 Fc-tagged CHO Fc
    Human CD27-079HG GMP Recombinant Human CD27 protein, Fc-tagged HEK293 Fc
    Human CD27-1079H Recombinant Human CD27 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human CD27-1079HA Recombinant Human CD27 protein, Fc-tagged, APC-labeled HEK293 Fc
    Human CD27-1079HP Recombinant Human CD27 protein, Fc-tagged, R-PE-labeled HEK293 Fc
    Human CD27-1383HCL Recombinant Human CD27 cell lysate Human Cell N/A
    Human CD27-141H Recombinant Human CD27, Fc-tagged CHO Fc
    Human CD27-1592H Recombinant Human CD27 Molecule, Fc-His Mammalian cells Fc/His
    Human CD27-180H Recombinant Human CD27 Protein, Fc-tagged HEK293 Fc
    Human CD27-26925TH Recombinant Human CD27 Wheat Germ N/A
    Human CD27-324H Recombinant Human CD27 Protein (Met1-Ile192), His-tagged, Biotinylated Insect Cell His
    Human CD27-336H Recombinant Human CD27 protein, His-tagged HEK293 His
    Human CD27-337H Recombinant Human CD27 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Human CD27-556H Recombinant Human CD27, His tagged Insect Cell Fc
    Human CD27-564H Recombinant Human CD27, Fc-tagged, Biotinylated Human Cell Fc
    Human CD27-56H Recombinant Human CD27 Molecule, Fc-Tagged Human Cell Fc
    Human CD27-572H Recombinant Human CD27 protein, His-tagged E.coli His
    Human CD27-57H Recombinant Human CD27 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human CD27-6271H Recombinant Human CD27 protein, His-tagged HEK293 His
    Human CD27-6351H Recombinant Human CD27 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CD27-638H Recombinant Human CD27, Fc-His tagged Human Cell Fc/His
    Human CD27-7139H Recombinant Human CD27 Molecule, His-tagged E.coli His
    Human CD27-887H Recombinant Human CD27 Protein, DDK/His-tagged HEK293 DDK/His
    Human CD27-888H Recombinant Human CD27 Protein, Fc/His-tagged HEK293 Fc/His
    Mouse Cd27-2058M Recombinant Mouse Cd27 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse CD27-2415MCL Recombinant Mouse CD27 cell lysate Human Cell N/A
    Mouse Cd27-3258M Recombinant Mouse CD27 Antigen, Fc Chimera Human Cell Fc
    Mouse Cd27-3273M Recombinant Mouse Cd27, His tagged Human Cell His
    Mouse CD27-357M Recombinant Mouse CD27 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Mouse Cd27-840M Recombinant Mouse Cd27 Protein, His & Fc-tagged HEK293 His/Fc
    Rat Cd27-643R Recombinant Rat Cd27, Fc Chimera Mammalian cells Fc Chimera
    Rat CD27-946R Recombinant Rat CD27 Protein (Met1-Arg183), HlgG1 Fc-tagged HEK293 HlgG1 Fc
    Rat CD27-947R Recombinant Rat CD27 Protein (Met1-Cys181), MlgG2a Fc-tagged HEK293 MlgG2a Fc
    Cynomolgus Monkey CD27-1156CCL Recombinant Cynomolgus CD27 cell lysate Human Cell N/A
    Rhesus monkey CD27-1654R Recombinant Rhesus Monkey CD27 Protein HEK293 N/A
    Rhesus Macaque CD27-493R Recombinant Rhesus CD27 protein, Fc-tagged HEK293 Fc
    Cynomolgus/Rhesus macaque CD27-335C Recombinant Cynomolgus/Rhesus macaque CD27 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc

    Cd27 involved in several pathways and played different roles in them. We selected most pathways Cd27 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction TNFSF11; FLT4; CXCL8; IFNA16; GM-CSF; IL5RA; CSF1R; IFNA6; CCR6A; CTF1

    Cd27 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cd27 itself. We selected most functions Cd27 had, and list some proteins which have the same functions with Cd27. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase inhibitor activity involved in apoptotic process TNFSF14; BIRC8; IGF1RA; RPS6KA1; CD27; DPEP1; TNFAIP8; TFAP2B; BIRC7; VIL1
    protein binding SRF; STYK1; CALCOCO1; ACLY; SRSF2; ASF1B; NTRK1; TLX1; JAM2A; APPBP2
    transmembrane signaling receptor activity FZD1; FCAMR; EMR4; GLP1R; GPR133; ANTXR1; TLR2-2; LGR6; NRXN2; CLDN4
    tumor necrosis factor-activated receptor activity TNFRSF9; TNFRSF10C; TNFRSF8; TNFRSF10B; TNFRSF4; EDA2R; TNFRSF11A; CD27; TNFRSF6B; TNFRSF10A

    Cd27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd27 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd27.


    Convers, KD; Kariuki, BM; et al. Decreased CD5(-)CD19(+)CD27(+)CD43(+)CD70(-) B-Cell Subpopulation in Children with Specific Antibody Deficiency. PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY 28:27-31(2015).
    Becerra, E; Scully, MA; et al. Effect of rituximab on B cell phenotype and serum B cell-activating factor levels in patients with thrombotic thrombocytopenic purpura. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 179:414-425(2015).

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