Recombinant Human CD79B protein, Fc-tagged
Cat.No. : | CD79B-239H |
Product Overview : | Recombinant Human CD79B protein (Ala29-Asp159), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
Availability | October 24, 2024 |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
- Download
Description : | B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type (immunoglobulin-like) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 41.8 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 131 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >92% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CD79B |
Official Symbol : | CD79B |
Synonyms : | CD79B; CD79b molecule, immunoglobulin-associated beta; CD79B antigen (immunoglobulin associated beta) , IGB; B-cell antigen receptor complex-associated protein beta chain; B29; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta); IGB; AGM6 |
Gene ID : | 974 |
mRNA Refseq : | NM_000626 |
Protein Refseq : | NP_000617 |
MIM : | 147245 |
UniProt ID : | P40259 |
Products Types
◆ Recombinant Protein | ||
Cd79b-1222M | Recombinant Mouse Cd79b Protein, MYC/DDK-tagged | +Inquiry |
Cd79b-8776R | Recombinant Rat Cd79b protein(Met1-Asp158), His-tagged | +Inquiry |
CD79B-0858H | Recombinant Human CD79B Protein, GST-Tagged | +Inquiry |
CD79B-699H | Recombinant Human CD79B Protein, His-tagged | +Inquiry |
CD79B-171H | Recombinant Human CD79B Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CD79B-1827MCL | Recombinant Mouse CD79B cell lysate | +Inquiry |
CD79B-1323RCL | Recombinant Rat CD79B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewRenowned for its reliability and consistency, this protein offers researchers the confidence to achieve accurate and reproducible results in their studies.
The CD79B protein comes highly recommended for its outstanding performance in ELISA assays.
One notable advantage of the CD79B protein is the excellent technical support provided by its manufacturer.
Q&As (5)
Ask a questionCD79B-targeted immunotherapy aims to specifically target B cells, potentially reducing side effects compared to non-specific chemotherapy.
Analyzing CD79B expression helps tailor treatment plans, allowing for more personalized and effective approaches.
Yes, monitoring CD79B levels can aid in detecting minimal residual disease, providing insights into treatment response.
Variability in CD79B expression among different B cell disorders may pose challenges in its use as a standalone diagnostic marker.
Yes, several clinical trials are exploring the efficacy of CD79B-targeted drugs in various B cell disorders.
Ask a Question for All CD79B Products
Required fields are marked with *
My Review for All CD79B Products
Required fields are marked with *
Inquiry Basket