Recombinant Human CD79b molecule, immunoglobulin-associated beta, His-tagged
Cat.No. : | CD79B-397H |
Product Overview : | CD79B, 29-159aa, Human, His tag, E.coli |
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Description : | CD79B, also known as Igb and B29, is a 36 kDa transmembrane glycoprotein in the immunoglobulin superfamily. Heterodimers of CD79A and CD79B associate with a membrane bound immunoglobulin on the B cell surface to form the B cell antigen receptor complex(BCR). CD79A and CD79B are required for BCR-mediated signaling and consequently for the development and activation of B lineage cells. Recombinant human CD79B protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M UREA, 10% glycerol |
Molecular Mass : | 17.7 kDa (155aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMARSEDR YRNPKGSACS RIWQSPRFIA RKRGFTVKMH CYMNSASGNV SWLWKQEMDE NPQQLKLEKG RMEESQNESL ATLTIQGIRF EDNGIYFCQQ KCNNTSEVYQ GCGTELRVMG FSTLAQLKQR NTLKD |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Protein length : | 29-159 |
Gene Name : | CD79B CD79b molecule, immunoglobulin-associated beta [ Homo sapiens ] |
Official Symbol : | CD79B |
Synonyms : | CD79B; CD79b molecule, immunoglobulin-associated beta; CD79B antigen (immunoglobulin associated beta) , IGB; B-cell antigen receptor complex-associated protein beta chain; B29; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta); IGB; AGM6; |
Gene ID : | 974 |
mRNA Refseq : | NM_000626 |
Protein Refseq : | NP_000617 |
MIM : | 147245 |
UniProt ID : | P40259 |
Chromosome Location : | 17q23 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Immune System, organism-specific biosystem; |
Function : | transmembrane signaling receptor activity; |
Products Types
◆ Recombinant Protein | ||
CD79B-3113H | Recombinant Human CD79B Protein, MYC/DDK-tagged | +Inquiry |
CD79B-209H | Recombinant Human CD79B Protein, C-His-tagged | +Inquiry |
Cd79b-1222M | Recombinant Mouse Cd79b Protein, MYC/DDK-tagged | +Inquiry |
CD79B-171H | Recombinant Human CD79B Protein, Fc-tagged | +Inquiry |
CD79B-699H | Recombinant Human CD79B Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CD79B-1827MCL | Recombinant Mouse CD79B cell lysate | +Inquiry |
CD79B-1323RCL | Recombinant Rat CD79B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewRenowned for its reliability and consistency, this protein offers researchers the confidence to achieve accurate and reproducible results in their studies.
The CD79B protein comes highly recommended for its outstanding performance in ELISA assays.
One notable advantage of the CD79B protein is the excellent technical support provided by its manufacturer.
Q&As (5)
Ask a questionCD79B-targeted immunotherapy aims to specifically target B cells, potentially reducing side effects compared to non-specific chemotherapy.
Analyzing CD79B expression helps tailor treatment plans, allowing for more personalized and effective approaches.
Yes, monitoring CD79B levels can aid in detecting minimal residual disease, providing insights into treatment response.
Variability in CD79B expression among different B cell disorders may pose challenges in its use as a standalone diagnostic marker.
Yes, several clinical trials are exploring the efficacy of CD79B-targeted drugs in various B cell disorders.
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