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CHRNA1

  • Official Full Name

    cholinergic receptor, nicotinic, alpha 1 (muscle)

  • Overview

    The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively
  • Synonyms

    CHRNA1; cholinergic receptor, nicotinic, alpha 1 (muscle); cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) , CHRNA; acetylcholine receptor subunit alpha; acetylcholine receptor; nicotinic; alpha 1 (muscle); nicotinic cholinergic receptor alp;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Pacific electric ray
  • Rat
  • Tetronarce Californica
  • Torpedo californica
  • Torpedo Californica
  • Zebrafish
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • His|SUMOstar
  • His|T7
  • PDI
  • Trx
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHRNA1-30388TH Recombinant Human CHRNA1 Wheat Germ N/A 86 amino acids
Human CHRNA1-1277H Recombinant Human CHRNA1 Protein, GST-Tagged Wheat Germ GST
Human CHRNA1-125H Recombinant Human CHRNA1 protein, His-tagged E.coli His
Human CHRNA1-5695H Recombinant Human CHRNA1 protein, His & T7-tagged E.coli His/T7 Pro256~Ile341 (Accession # P02708)
Human CHRNA1-7517HCL Recombinant Human CHRNA1 293 Cell Lysate HEK293 N/A
Human CHRNA1-2694H Recombinant Human CHRNA1 protein, His-tagged E.coli His 21-255aa
Human CHRNA1-5379H Recombinant Human CHRNA1 protein, His-PDI-tagged Yeast His-PDI 21-255aa
Human CHRNA1-3225HF Recombinant Full Length Human CHRNA1 Protein, GST-tagged In Vitro Cell Free System GST 457 amino acids
Human CHRNA1-1721H Recombinant Human CHRNA1 Protein (Pro256-Ile341), N-GST tagged E.coli N-GST Pro256-Ile341
Human CHRNA1-2695H Recombinant Human CHRNA1 protein, His-Trx-tagged E.coli His-Trx 21-255aa
Mouse Chrna1-3053M Recombinant Mouse Chrna1, His-tagged E.Coli or Yeast His 457
Mouse CHRNA1-3429M Recombinant Mouse CHRNA1 Protein Mammalian Cell His
Mouse Chrna1-2696M Recombinant Mouse Chrna1 protein, His-tagged E.coli His 21-230aa
Mouse CHRNA1-406M Recombinant Mouse CHRNA1 Protein (21-230 aa), His-SUMO-tagged E.coli His/SUMO 21-230 aa
Mouse Chrna1-5380M Recombinant Mouse Chrna1 protein, His-tagged Yeast His 21-230aa
Mouse CHRNA1-1662M Recombinant Mouse CHRNA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CHRNA1-1662M-B Recombinant Mouse CHRNA1 Protein Pre-coupled Magnetic Beads HEK293
Rat CHRNA1-1389R Recombinant Rat CHRNA1 Protein Mammalian Cell His
Rat CHRNA1-1047R-B Recombinant Rat CHRNA1 Protein Pre-coupled Magnetic Beads HEK293
Rat CHRNA1-1047R Recombinant Rat CHRNA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Chrna1-778R Recombinant Rat Chrna1 Protein, His-tagged E.coli N-His Ser21-Phe245
Pacific electric ray CHRNA1-408T Recombinant Pacific electric ray CHRNA1 protein E.coli His 25-234a
Pacific electric ray CHRNA1-1472P Recombinant Pacific electric ray CHRNA1 protein, His-tagged HEK293 His 25-234aa
Tetronarce Californica CHRNA1-2696T Recombinant Tetronarce Californica CHRNA1 Protein (25-234 aa), His-sumostar-tagged Yeast His/SUMOstar 25-234 aa
Torpedo californica CHRNA1-1515T Recombinant Torpedo californica CHRNA1 protein, His-tagged Insect Cell His 25-234aa
Torpedo Californica CHRNA1-407T Recombinant Torpedo Californica CHRNA1 Protein (25-234 aa), His-SUMO-tagged E.coli His/SUMO 25-234 aa
Zebrafish CHRNA1-9013Z Recombinant Zebrafish CHRNA1 Mammalian Cell His
Chicken CHRNA1-6379C Recombinant Chicken CHRNA1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CHRNA1 Related Research Area

CHRNA1 involved in several pathways and played different roles in them. We selected most pathways CHRNA1 participated on our site, such as Acetylcholine Binding And Downstream Events, Activation of Nicotinic Acetylcholine Receptors, Effects of Botulinum toxin, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHRNA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Acetylcholine Binding And Downstream EventsCHRNB2;CHRND;CHRNA2;CHRNE;CHRNA5;CHRNA4;CHRNA7;CHRNA1;CHRNB4
Activation of Nicotinic Acetylcholine ReceptorsCHRNA7;CHRNB4;CHRNA3;CHRNA4;CHRNA1;CHRNA5;CHRNB2;CHRND;CHRNE
Effects of Botulinum toxinCCDC167;CHRNA1;RAB3GAP2;UNC13B
ErbB2/ErbB3 signaling eventsDOCK7;CHRNA1;RNF41;CHRNE;FMNL3
Highly calcium permeable nicotinic acetylcholine receptorsCHRNA1;CHRNA2;CHRNA3;CHRNB4;CHRNB2;CHRNA4;CHRNA5
Highly calcium permeable postsynaptic nicotinic acetylcholine receptorsCHRNA4;CHRNB4;CHRNA7;CHRNA5;CHRNB2;CHRNA2;CHRNA1;CHRNA3
Neuroactive ligand-receptor interactionPLG;HRH4;GNRHR;GRIN2BB;P2RX6;PTGER1B;ADRA2DB;VIPR1;CHRNA1
Neuronal SystemLIN7C;KCNH1;KCNAB1;KCNK7;MYO6;KCND1;KCNA5;SLC6A12;SLC1A3A

CHRNA1 has several biochemical functions, for example, contributes_to acetylcholine binding, contributes_to acetylcholine receptor activity, acetylcholine-activated cation-selective channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHRNA1 itself. We selected most functions CHRNA1 had, and list some proteins which have the same functions with CHRNA1. You can find most of the proteins on our site.

Function Related Protein
contributes_to acetylcholine bindingCHRNA1;CHRNA3;CHRNA10;CHRNB3A;CHRNE;CHRNA10A;CHRNB4;CHRNA6;CHRNB1L
contributes_to acetylcholine receptor activityCHRNA10;CHRND;CHRNB1L;CHRNA9;CHRNB3A;CHRFAM7A;CHRNB3B;CHRNB1;ZACN
acetylcholine-activated cation-selective channel activityCHRNB3B;CHRNB2;CHRNB1L;CHRNA1;CHRNA4B;Chrng;CHRNA2A;CHRND;CHRNA3
contributes_to acetylcholine-activated cation-selective channel activityCHRNB3B;CHRNA4B;CHRNA9;CHRNA1;CHRFAM7A;CHRNA10A;CHRNA2A;CHRNB1;CHRNA10
ion channel activityKCNH2A;TRPC2B;CLCN3;KCNH6A;SCN1LAB;GJD3;CLCN6;CHRNB3A;CHRNB3

CHRNA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHRNA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHRNA1.

CHRNB1; CHRNG; chrnd

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