Recombinant Human CHRNA1 Protein, GST-Tagged

• Cat.No.: CHRNA1-1277H
• Product Overview: Human CHRNA1 full-length ORF (BAG37716.1, 1 a.a. - 457 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 76.67 kDa
• AA Sequence: MEPWPLLLLFSLCSAGLVLGSEHET RLVAKLFKDYSSVVRPVEDHRQVVE VTVGLQLIQLINVDEVNQIVTTNVR LKQQWVDYNLKWNPDDYGGVKKIHI PSEKIWRPDLVLYNNADGDFAIVKF TKVLLQYTGHITWTPPAIFKSYCEI IVTHFPFDEQNCSMKLGTWTYDGSV VAINPESDQPDLSNFMESGEWVIKE SRGWKHSVTYSCCPDTPYLDITYHF VMQRLPLYFIVNVIIPCLLFSFLTG LVFYLPTDSGEKMTLSISVLLSLTV FLLVIVELIPSTSSAVPLIGKYMLF TMVFVIASIIITVIVINTHHRSPST HVMPNWVRKVFIDTIPNIMFFSTMK RPSREKQDKKIFTEDIDISDISGKP GPPPMGFHSPLIKHPEVKSAIEGIK YIAETMKSDQESNNAAAEWKYVAMV MDHILLGVFMLVCIIGTLAVFAGRL IELNQQG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) [ Homo sapiens ]
• Official Symbol: CHRNA1
• Synonyms: CHRNA1; cholinergic receptor, nicotinic, alpha 1 (muscle); cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), CHRNA; acetylcholine receptor subunit alpha; acetylcholine receptor; nicotinic; alpha 1 (muscle); nicotinic cholinergic receptor alpha 1; muscle nicotinic acetylcholine receptor; nicotinic acetylcholine receptor alpha subunit; acetylcholine receptor, nicotinic, alpha 1 (muscle); cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle); ACHRA; ACHRD; CHRNA; CMS2A; FCCMS; SCCMS
• Gene ID: 1134
• mRNA Refseq: NM_000079
• Protein Refseq: NP_000070
• MIM: 100690
• UniProt ID: P02708