Recombinant Human CXCL11 protein
| Cat.No. : | CXCL11-280H |
| Product Overview : | Recombinant Human CXCL11 protein was expressed in Escherichia coli. |
- Specification
- Gene Information
- Related Products
| Description : | CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36 % and 37 % amino acid sequence homology with IP-10 and MIG, respectively. It is highly expressed in peripheral blood leukocytes, pancreas and liver. Expression of CXCL11 is strongly induced by IFN-γ and IFN-β, and weakly induced by IFN-α. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3, which with a higher affinity than do the other chemokines for this receptor, CXCL9 and CXCL10. Similar to CXCL10, CXCL11 has been shown to be a chemoattractant for IL-2-activated T-lymphocytes, but not for isolated T-cells, neutrophils or monocytes. |
| Source : | E.coli |
| Species : | Human |
| Form : | Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl. |
| Bio-activity : | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10 ng/ml. |
| Molecular Mass : | Approximately 8.3 kDa, a single non-glycosylated polypeptide chain containing 73 amino acids. |
| Protein length : | 73 |
| AA Sequence : | FPMFKRGRCLCIGPGVKAVKVADIE KASIMYPSNNCDKIEVIITLKENKG QRCLNPKSKQARLIIKKVERKNF |
| Endotoxin : | Less than 1 EU/µg of rHuI-TAC/CXCL11 as determined by LAL method. |
| Purity : | >97% by SDS-PAGE and HPLC analysis. |
| Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
| Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
| Gene Name : | CXCL11 |
| Official Symbol : | CXCL11 |
| Synonyms : | CXCL11; chemokine (C-X-C motif) ligand 11; SCYB9B, SCYB11, small inducible cytokine subfamily B (Cys X Cys), member 11; C-X-C motif chemokine 11; b R1; H174; I TAC; IP 9; beta-R1; small inducible cytokine B11; small-inducible cytokine B11; interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; IP9; IP-9; b-R1; I-TAC; SCYB11; SCYB9B; MGC102770; |
| Gene ID : | 6373 |
| mRNA Refseq : | NM_005409 |
| Protein Refseq : | NP_005400 |
| MIM : | 604852 |
| UniProt ID : | O14625 |
Products Types
| ◆ Recombinant Protein | ||
| CXCL11-806M | Recombinant Mouse CXCL11 Protein (Phe22-Met100), His-tagged | +Inquiry |
| Cxcl11-2773H | Recombinant Hamster Cxcl11 Protein, His-tagged | +Inquiry |
| CXCL11-201B | Recombinant Bovine CXCL11 Protein, His-tagged | +Inquiry |
| CCL11-01H | Recombinant Human CXCL11 Protein, DYKDDDDK-tagged | +Inquiry |
| CXCL11-931R | Recombinant Rhesus Macaque CXCL11 Protein, His (Fc)-Avi-tagged | +Inquiry |
| ◆ Lysates | ||
| CXCL11-7171HCL | Recombinant Human CXCL11 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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