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Official Full Name Fc fragment of IgG, low affinity IIa, receptor (CD32)
Background This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
Synonyms FCGR2A; Fc fragment of IgG, low affinity IIa, receptor (CD32); CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1
    • Species :
    • Cynomolgus Monkey
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • Cynomolgus
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • Avi
    • His-Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FCGR2A-001HCL Recombinant Human FCGR2A cell lysate CHO N/A
    Human FCGR2A-1136H Recombinant Human FCGR2A, His & AVI tagged Human Cell His/Avi
    Human FCGR2A-12819H Recombinant Human FCGR2A, GST-tagged E.coli GST
    Human FCGR2A-161H Recombinant Human FCGR2A, His-tagged NS0 His
    Human FCGR2A-1996HCL Recombinant Human FCGR2A cell lysate Human Cell N/A
    Human FCGR2A-259H Recombinant Human FCGR2A, His-tagged, Biotinylated HEK293 His
    Human FCGR2A-260H Recombinant Human FCGR2A Protein, His-tagged, Biotinylated HEK293 His
    Human FCGR2A-2963H Recombinant Human FCGR2A, His & AVI Tagged, Biotinylated, 167 His Human Cell His/Avi
    Human FCGR2A-2964H Recombinant Human FCGR2A, His & AVI Tagged, Biotinylated, 167 Arg Human Cell His/Avi
    Human FCGR2A-3074H Recombinant Human FCGR2A, His tagged Insect Cell His
    Human FCGR2A-3130H Recombinant Human FCGR2A, Fc tagged Human Cell Fc
    Human FCGR2A-313HB Recombinant Human FCGR2A protein(V176), His-Avi-tagged, Biotinylated HEK293 His-Avi
    Human FCGR2A-333H Recombinant Human FCGR2A(H167) protein, His-Avi-tagged HEK293 His-Avi
    Human FCGR2A-352H Recombinant Human FCGR2A protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human FCGR2A-383H Recombinant Human FCGR2A Protein (H167), His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human FCGR2A-384H Recombinant Human FCGR2A Protein (R167) (Ala 36 - Ile 218), His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human FCGR2A-3990H Recombinant Human FCGR2A Protein Wheat Germ N/A
    Human FCGR2A-3992H Recombinant Human FCGR2A Protein, GST-tagged Wheat Germ GST
    Human FCGR2A-399H Recombinant Human FCGR2A, His-tagged CHO His
    Human FCGR2A-513HB Recombinant Human FCGR2A protein(F176), His-Avi-tagged, Biotinylated HEK293 His-Avi
    Human FCGR2A-649H Recombinant Human FCGR2A protein(167 Arg), His-tagged HEK293 His
    Human FCGR2A-678HCL Recombinant Human FCGR2A cell lysate Insect Cell N/A
    Human FCGR2A-7236H Recombinant Human FCGR2A, His-tagged E.coli His
    Rat FCGR2A-2305R Recombinant Rat FCGR2A Protein Mammalian Cell His
    Rat Fcgr2a-4939R Recombinant Rat Fcgr2a protein, Fc-tagged HEK293 Fc
    Rat FCGR2A-932R Recombinant Rat FCGR2A Protein (Met1-Leu216), His-tagged HEK293 His
    Cynomolgus Monkey FCGR2A-1926CCL Recombinant Cynomolgus FCGR2A cell lysate Human Cell N/A
    Cynomolgus Monkey FCGR2A-270C Recombinant Cynomolgus Monkey FCGR2A protein, His-tagged HEK293 His
    Cynomolgus Monkey FCGR2A-2973C Recombinant Cynomolgus FCGR2A, His & AVI tagged Human Cell His/Avi
    Cynomolgus Monkey FCGR2A-4107C Recombinant Cynomolgus FCGR2A, His tagged Human Cell His
    Cynomolgus Monkey FCGR2A-4108C Recombinant Cynomolgus Fc Fragment Of LgG, Low Affinity LIa, Receptor (CD32), AVI-tagged Cynomolgus N/A
    Cynomolgus Monkey FCGR2A-519C Recombinant Cynomolgus FCGR2A Protein, His-tagged Mammalian Cell His
    Rhesus Macaque FCGR2A-4111C Recombinant Rhesus FCGR2A protein, His-tagged HEK293 His

    fcgr2a involved in several pathways and played different roles in them. We selected most pathways fcgr2a participated on our site, such as Phagosome, Osteoclast differentiation, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with fcgr2a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome HLA-A; C3A.1; CD209B; COLEC12; TUBA3A; ABCB3L1; MHC2DAB; TUBA2; TUBAL3; HLA-DOB
    Osteoclast differentiation MAPK9; NOX3; OSCAR; MAP2K6; IFNGR2; FYN; SPI1; SIRPB1; BLNK; TGFB2
    Platelet activation ITGB1; GNAI2; PIK3CD; PRKCZ; ORAI1; ITGA2B; F2R; PRKACG; PIK3CA; PIK3R2
    Fc gamma R-mediated phagocytosis WASL; PLA2G6; RPS6KB2; BIN1; GAB2; NCF1; PAK1; PPAP2A; PLA2G4F; PLCG2
    Leishmaniasis CR1; HLA-DQA1; IL1A; NFKBIB; TGFB1; PTGS2; TLR4; ITGAM; HLA-DRB1; FOS
    Staphylococcus aureus infection ITGB2L; C2; ITGAM; SELPLG; DSG1A; PLG; FCAR; HLA-DMB; FPR1; HLA-DQB1
    Tuberculosis IFNA14; CD209; TGFB1; RHOA; IFNA17; PPP3R2; PPP3CB; MAPK3; TRAF6; TNF
    Systemic lupus erythematosus IFNG; Hc; HIST1H2BK; HIST1H2AA; HIST2H4A; HLA-DQA2; HLA-DRB3; H2AFY; HLA-DRB5; GM5077

    fcgr2a has several biochemical functions, for example, IgG binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fcgr2a itself. We selected most functions fcgr2a had, and list some proteins which have the same functions with fcgr2a. You can find most of the proteins on our site.

    Function Related Protein
    IgG binding FCER1G; UMOD; CD247L; FCGR1; FCGR3A; FCGR2C; PIP; FCGR1B; FCGR2B; cgr2b
    protein binding FAM118A; ETV7; PHLDA1; SUDS3; PID1; CASR; SENP1; HSCB; CAV2; PSMB7

    fcgr2a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fcgr2a here. Most of them are supplied by our site. Hope this information will be useful for your research of fcgr2a.

    UBQLN1; UBQLN1; drozitumab; CRP; SYK

    Carmona, FD; Martin, J; et al. Genetics of vasculitis. CURRENT OPINION IN RHEUMATOLOGY 27:10-17(2015).
    Amirkhosravi, A; Boulaftali, Y; et al. CalDAG-GEFI deficiency protects mice from Fc gamma RIIa-mediated thrombotic thrombocytopenia induced by CD40L and beta 2GPI immune complexes. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 12:2113-2119(2014).

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