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Recombinant Rat Fcgr2a protein, Fc-tagged

Cat.No. : Fcgr2a-4939R
Product Overview : Recombinant Rat Fcgr2a(Met1-Leu216) fused with Fc region of human IgG1 at C-terminal was expressed in HEK293.
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Description : Fcgr2a played an important role in many functions.
Source : HEK293
Species : Rat
Tag : Fc
Predicted N Terminal : Asp 32
Form : Lyophilized from sterile PBS, pH 7.4.1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.2. Please contact us for any concerns or special requirements.
Molecular Mass : The recombinant rat FCGR2A consists 423 amino acids and predicts a molecular mass of 47.5 kDa.
Protein length : Met1-Leu216
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 85 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : Fcgr2a Fc fragment of IgG, low affinity IIa, receptor (CD32) [ Rattus norvegicus ]
Official Symbol : Fcgr2a
Synonyms : FCGR2A; Fc fragment of IgG, low affinity IIa, receptor (CD32); low affinity immunoglobulin gamma Fc region receptor III; fcRIII; fc-gamma RIII; igG Fc receptor III; Fc receptor, IgG, low affinity III; Fc fragment of IgG low affinity IIa receptor for (CD32); Fcgr3; Fcgr3a;
Gene ID : 116591
mRNA Refseq : NM_053843
Protein Refseq : NP_446295
UniProt ID : P27645
Chromosome Location : 13q24
Pathway : Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; Leishmaniasis, organism-specific biosystem; Leishmaniasis, conserved biosystem; Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem; Osteoclast differentiation, organism-specific biosystem;
Function : IgG binding; IgG receptor activity; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does FCGR2A impact the risk and severity of certain allergic reactions? 03/22/2023

FCGR2A may influence the risk and severity of allergic reactions by modulating the immune response to allergens and antibodies involved in allergic processes.

In the context of infectious diseases, how does FCGR2A contribute to host defense mechanisms? 11/02/2022

FCGR2A participates in host defense against infectious diseases by facilitating the recognition and clearance of pathogens through antibody-mediated immune responses.

How does FCGR2A contribute to the understanding of immunogenetics? 05/26/2021

FCGR2A contributes to the understanding of immunogenetics by highlighting the genetic factors that influence immune responses and the development of immune-related diseases.

How can genetic variations in FCGR2A impact an individual's response to immunotherapy? 03/10/2020

Genetic variations in FCGR2A can influence an individual's response to immunotherapy by affecting the affinity of FCGR2A for antibodies, thereby modulating immune cell activation.

In what ways can FCGR2A be targeted for therapeutic interventions? 12/11/2017

FCGR2A can be targeted for therapeutic interventions through the development of drugs that modulate its activity, offering potential strategies for treating immune-related disorders.

Customer Reviews (3)

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Reviews
03/22/2023

    With its purity and reliability, this protein is poised to contribute significantly to the success of my research objectives by providing accurate and reproducible results.

    02/26/2023

      Its versatility allows for exploration of its extensive involvement in various biochemical and biological processes, providing valuable insights into its role and implications.

      07/24/2017

        The FCGR2A Protein demonstrates remarkable stability and functional efficiency, making it an indispensable tool for diverse scientific applications.

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