HSP90AA1

  • Official Full Name

    heat shock protein 90kDa alpha (cytosolic), class A member 1

  • Overview

    The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  • Synonyms

    HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1; EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; HSPCAL1; HSPCAL4; heat shock protein HSP 90-alpha; HSP 86; heat shock 86 kDa; LPS-associated protein 2; heat shock 90kD protein 1, alpha; heat shock 90kDa protein 1, alpha; renal carcinoma antigen NY-REN-38; heat shock 90kD protein, alpha-like 4; epididymis luminal secretory protein 52; heat shock 90kD protein 1, alpha-like 4; lipopolysaccharide-associated protein 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Native Proteins
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Pig
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • HeLa
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Yeast
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|MBP
  • SUMO
  • MYC
  • Myc|DDK
  • N/A
  • N
  • 6×His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSP90AA1-70H Active Recombinant Human HSP90AA1 E.coli N/A
Human HSP90AA1-136H Recombinant Human HSP90AA1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HSP90AA1-227H Recombinant Human HSP90AA1 Mammalian Cell His
Human HSP90AA1-318H Recombinant Human Heat Shock Protein 90kDa Alpha (Cytosolic), Class A Member 1 E.coli His
Human HSP90AA1-27845TH Recombinant Human HSP90AA1, His-tagged E.coli His
Human HSP90AA1-137H Recombinant Human HSP90AA1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HSP90AA1-27844TH Recombinant Human HSP90AA1, His-tagged E.coli His
Human HSP90AA1-27843TH Recombinant Human HSP90AA1 E.coli N/A
Human HSP90AA1-1461H Recombinant Human HSP90AA1, His-tagged Sf9 Insect Cell His
Human HSP90AA1-3097H Recombinant Human HSP90AA1 protein(Glu535-Asp732) E.coli N/A Glu535-Asp732
Human HSP90AA1-266H Recombinant Human HSP90AA1 protein, His/MBP-tagged E.coli His/MBP 727-854 aa
Human HSP90AA1-28996TH Recombinant Human HSP90AA1, His-tagged E.coli His
Human HSP90AA1-135H Recombinant Human Heat Shock Protein 90kDa Alpha (cytosolic), Class A Member 1, His-tagged E.coli His
Human HSP90AA1-28997TH Recombinant Human HSP90AA1 protein, His-tagged Insect Cell His
Human HSP90AA1-1561H Recombinant Human HSP90AA1 protein E.coli N/A
Human HSP90AA1-267H Recombinant Human HSP90AA1 protein, His/MBP-tagged E.coli His/MBP 549-692 aa
Human HSP90AA1-27081TH Recombinant Human HSP90AA1 E.coli N/A
Human HSP90AA1-269H Recombinant Human HSP90AA1 protein, His/MBP-tagged E.coli His/MBP 1-140 aa
Human HSP90AA1-268H Recombinant Human HSP90AA1 protein, His/MBP-tagged E.coli His/MBP 275-448 aa
Human HSP90AA1-5362HCL Recombinant Human HSP90AA1 293 Cell Lysate HEK293 N/A
Human HSP90AA1-1113H-B Recombinant Human HSP90AA1 Protein Pre-coupled Magnetic Beads HEK293
Human HSP90AA1-049H Recombinant Human HSP90AA1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human HSP90AA1-03H Recombinant Human HSP90AA1 protein, His-tagged E.coli His 1-291aa
Human HSP90AA1-14H Native Hsp90 Protein HeLa N/A
Human HSP90AA1-366H Recombinant Human HSP90AA1 protein, GST-tagged E.coli GST 198
Human HSP90AA1-3055H Recombinant Human HSP90AA1 protein, His-SUMO-tagged E.coli His-SUMO 9-232aa
Human HSP90AA1-05H Recombinant Human HSP90AA1 protein, His-tagged Yeast His 9-232aa
Human HSP90AA1-3853H Recombinant Human HSP90AA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HSP90AA1-1342H Recombinant Human HSP90AA1 protein, His-tagged E.coli His 1-291aa
Human HSP90AA1-04H Recombinant Human HSP90AA1 protein, His-tagged E.coli His 292-559aa
Human HSP90AA1-1113H Recombinant Human HSP90AA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HSP90AA1-01H Recombinant Human HSP90AA1 protein, His-SUMO-tagged E.coli His-SUMO 9-232aa
Human HSP90AA1-1343H Recombinant Human HSP90AA1 protein, His-tagged E.coli His 292-559aa
Human HSP90AA1-2641H Recombinant Human HSP90AA1 Protein (Met1-Asp732), N-His tagged E.coli N-His Met1-Asp732
Human HSP90AA1-02H Recombinant Human HSP90AA1 protein, His-tagged E.coli His 233-291aa
Human HSP90AA1-987HFL Recombinant Full Length Human HSP90AA1 Protein, C-Flag-tagged Mammalian cells Flag
Human HSP90AA1-047H Recombinant Human HSP90AA1 Protein, N-6×His-tagged E.coli N-6×His 732
Human HSP90AA1-2642H Recombinant Human HSP90AA1 Protein (Glu25-Gly697), GST tagged E.coli GST Glu25-Gly697
Mouse Hsp90aa1-32M Recombinant Mouse Hsp90aa1 protein, His-tagged E.coli His
Mouse HSP90AA1-7897M Recombinant Mouse HSP90AA1 Protein Mammalian Cell His
Mouse HSP90AA1-4349M Recombinant Mouse HSP90AA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hsp90aa1-1190M Recombinant Mouse Hsp90aa1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HSP90AA1-4349M-B Recombinant Mouse HSP90AA1 Protein Pre-coupled Magnetic Beads HEK293
Rat HSP90AA1-2939R Recombinant Rat HSP90AA1 Protein Mammalian Cell His
Rat HSP90AA1-2594R Recombinant Rat HSP90AA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HSP90AA1-2594R-B Recombinant Rat HSP90AA1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey HSP90AA1-604C Recombinant Cynomolgus HSP90AA1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey HSP90AA1-350C Recombinant Cynomolgus Monkey HSP90AA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey HSP90AA1-350C-B Recombinant Cynomolgus Monkey HSP90AA1 Protein Pre-coupled Magnetic Beads HEK293
Pig HSP90AA1-1246P Recombinant Pig HSP90AA1 Protein, His-tagged Insect Cell His
Chicken HSP90AA1-3762C Recombinant Chicken HSP90AA1 Mammalian Cell His
HSP90aA1-2695 Recombinant HSP90aA1 Protein, His-tagged E.coli N-His Met1-Gly496+Ile698-Asp732
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

HSP90AA1 involved in several pathways and played different roles in them. We selected most pathways HSP90AA1 participated on our site, such as Protein processing in endoplasmic reticulum, PIK-Akt signaling pathway, Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSP90AA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Protein processing in endoplasmic reticulumMBTPS2;ERN1;SEC61AL2;HSPA2;NFE2L2;SEC61A1;UBE2G1A;DNAJB12A;SSR4
PIK-Akt signaling pathwayTEK;Reln;GNG10;THBS2;FGF7;FLT1;INS2;IFNA6;Il2
Antigen processing and presentationHLA-G;NFYC;PSME1;HLA-DRA;NFYB;KIR2DS4;RFXAP;HLA-A;KIR3DL2
NOD-like receptor signaling pathwayNFKB1;NFKBIAB;CCL5;CASP8;CARD9;CXCL8B.3;IL8L2;CXCL1;MAP3K7
Progesterone-mediated oocyte maturationHSP90AA1;MAPK8B;GNAI2;MAPK14A;PRKACBA;GNAI2B;CPEB4;RPS6KA3B;MAPK11
Estrogen signaling pathwayKCNJ6;CALML3;ESR2;GABBR2;CALM1;ATF4;MAPK3;SHC2;MAPK1
Pathways in cancerHRAS;FH1;PRKACG;PAX8;PRKCG;MLH1;MAPK10;STAT3;FZD10
Prostate cancerNKX3;LEF1;FOXO1;CCNE2;HRAS;NKX3-1;MAP2K1;INS2;MAP4K1

HSP90AA1 has several biochemical functions, for example, ATP binding, ATPase activity, GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSP90AA1 itself. We selected most functions HSP90AA1 had, and list some proteins which have the same functions with HSP90AA1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTTLL9;UHMK1;CLK2;ERN2;NUBPL;YME1L1;GSK3B;SGK196;TTBK2
ATPase activityOLA1;Abca2;SMARCA5;KIFC2;NSF;ABCE1;DYNC1H1;KIF2C;ABCA5
GTPase bindingSPTBN1;YBX1;ENO1;BNIP3;EPRS;STOML2;VPS41;GOLGA4;GNB3
MHC class II protein complex bindingYWHAE;PKM;ANXA11;CD81;HSP90AA1;HSPA8;CD74;MS4A1;PKM2
TPR domain bindingRAB8B;HSP90AB1;PDE2A;HSP90AA1;STUB1
identical protein bindingAPLP1;SCHIP1;GAPDH;PFKFB1;DPP9;VEGFA;KCNRG;G6PDX;PPP1R13L
nitric-oxide synthase regulator activityHSP90AA1;ESR1;CALM2;HSP90AB1;CALM3;AKT1;HSP90AA1.1;CALM1
nucleotide bindingRNPC3;AKT2L;G3BP2;TRNAU1APB;cka1;TLK1A;UBE2IB;EPHA4A;EGFRA
poly(A) RNA bindingSAMD4B;EIF4E;MRPL14;PPIB;TNS1;RBM6;RRP12;NOM1;FAM32A
protein bindingCSNK1G2;NHP2L1;ZNF614;PSTPIP1;METTL1;TMEM64;OSBP;Ar;SPOPL
protein homodimerization activityTRIM37;GSTM2;GHR;DMRT2B;NLRC4;ECE1;HES1;BMPR1A;CSF1
unfolded protein bindingNAP1L4;UGGT1;GRPEL1;APCS;CLGN;HSP90AA1.1;CDC37L1;DNAJB1B;CLPXA

HSP90AA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSP90AA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSP90AA1.

CDC37; STUB1

  • Q&As
  • Reviews

Q&As (6)

Ask a question
What is the relationship between HSP90AA1 protein and inflammatory diseases? 12/08/2019

HSP90AA1 proteins can participate in regulating the expression and function of inflammatory factors in the inflammatory process, which has an impact on the occurrence and development of inflammatory diseases.

What is the role of HSP90AA1 protein in immunotherapy? 10/12/2019

HSP90AA1 proteins can help immune cells fold and activate some important antigens, participate in the immune response process, and have an impact on tumor immunotherapy.

Which fuction of HSP90AA1 protein in tumor diagnosis? 04/18/2019

The expression level of HSP90AA1 protein is upregulated in some tumor cells and can serve as a potential tumor biomarker for tumor diagnosis and monitoring.

Can HSP90AA1 protein be used as a therapeutic target for inflammatory diseases? 04/08/2019

There is no clear evidence that HSP90AA1 protein can be used as a therapeutic target for inflammatory diseases, but its regulatory role in the inflammatory process may provide new ideas for the development of related therapeutic strategies.

What is the relationship between HSP90AA1 protein and tumor drug resistance? 04/04/2019

HSP90AA1 proteins can lead to the occurrence and development of tumor drug resistance by stabilizing and protecting some resistance-related proteins, such as ABC transporters.

How to use HSP90AA1 protein to develop cancer therapeutics? 01/04/2019

Inhibitors targeting HSP90AA1 proteins can be developed to interfere with their interactions with other proteins, affecting the growth and survival of tumor cells.

Customer Reviews (3)

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Reviews
04/03/2022

    This powerful biological activity of the protein combined with its high purity makes the experimental results extremely reliable.

    02/10/2020

      Application range of this protein is really wide, from the laboratory to the clinic, can see its figure, it is really rare.

      08/08/2019

        Short half-life and high clearance of recombinant proteins enable them to effectively avoid drug accumulation and side effects, and provide a strong guarantee for patient safety.

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