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Recombinant Human HSP90AA1 protein, GST-tagged

Cat.No. : HSP90AA1-366H
Product Overview : Recombinant Human HSP90AA1 protein (Glu535-Asp732), fused to GST tag at N-terminus, was expressed in E.coli.
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  • Gene Information
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Description : Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Source : E.coli
Species : Human
Tag : GST
Form : Lyophilized from 0.22 um filtered solution in 50 mM HEPES, 150 mM NaCl, pH7.0, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 49.3 kDa. The protein migrates as 49 kDa under reducing (R) condition (SDS-PAGE).
Protein length : 198
Endotoxin : Less than 1.0 EU per ug by the LAL method.
Purity : >85% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : HSP90AA1
Official Symbol : HSP90AA1
Synonyms : HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock 90kD protein 1, alpha , heat shock 90kDa protein 1, alpha , HSPC1, HSPCA; heat shock protein HSP 90-alpha; FLJ31884; Hsp89; Hsp90; HSP90N; HSP 86; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kDa protein 1, alpha; renal carcinoma antigen NY-REN-38; heat shock 90kD protein, alpha-like 4; heat shock 90kD protein 1, alpha-like 4; HSPN; LAP2; HSP86; HSPC1; HSPCA; HSP89A; HSP90A; HSPCAL1; HSPCAL4
Gene ID : 3320
mRNA Refseq : NM_001017963
Protein Refseq : NP_001017963
MIM : 140571
UniProt ID : P07900

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the relationship between HSP90AA1 protein and inflammatory diseases? 12/08/2019

HSP90AA1 proteins can participate in regulating the expression and function of inflammatory factors in the inflammatory process, which has an impact on the occurrence and development of inflammatory diseases.

What is the role of HSP90AA1 protein in immunotherapy? 10/12/2019

HSP90AA1 proteins can help immune cells fold and activate some important antigens, participate in the immune response process, and have an impact on tumor immunotherapy.

Which fuction of HSP90AA1 protein in tumor diagnosis? 04/18/2019

The expression level of HSP90AA1 protein is upregulated in some tumor cells and can serve as a potential tumor biomarker for tumor diagnosis and monitoring.

Can HSP90AA1 protein be used as a therapeutic target for inflammatory diseases? 04/08/2019

There is no clear evidence that HSP90AA1 protein can be used as a therapeutic target for inflammatory diseases, but its regulatory role in the inflammatory process may provide new ideas for the development of related therapeutic strategies.

What is the relationship between HSP90AA1 protein and tumor drug resistance? 04/04/2019

HSP90AA1 proteins can lead to the occurrence and development of tumor drug resistance by stabilizing and protecting some resistance-related proteins, such as ABC transporters.

How to use HSP90AA1 protein to develop cancer therapeutics? 01/04/2019

Inhibitors targeting HSP90AA1 proteins can be developed to interfere with their interactions with other proteins, affecting the growth and survival of tumor cells.

Customer Reviews (3)

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Reviews
04/03/2022

    This powerful biological activity of the protein combined with its high purity makes the experimental results extremely reliable.

    02/10/2020

      Application range of this protein is really wide, from the laboratory to the clinic, can see its figure, it is really rare.

      08/08/2019

        Short half-life and high clearance of recombinant proteins enable them to effectively avoid drug accumulation and side effects, and provide a strong guarantee for patient safety.

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