Recombinant Full Length Human HSP90AA1 Protein, C-Flag-tagged

• Cat.No.: HSP90AA1-987HFL
• Product Overview: Recombinant Full Length Human HSP90AA1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 84.5 kDa
• AA Sequence: MPEETQTQDQPMEEEEVETFAFQAE IAQLMSLIINTFYSNKEIFLRELIS NSSDALDKIRYESLTDPSKL DSGKELHINLIPNKQDRTLTIVDTG IGMTKADLINNLGTIAKSGTKAFME ALQAGADISMIGQFGVGFYS AYLVAEKVTVITKHNDDEQYAWESS AGGSFTVRTDTGEPMGRGTKVILHL KEDQTEYLEERRIKEIVKKH SQFIGYPITLFVEKERDKEVSDDEA EEKEDKEEEKEKEEKESEDKPEIED VGSDEEEEKKDGDKKKKKKI KEKYIDQEELNKTKPIWTRNPDDIT NEEYGEFYKSLTNDWEDHLAVKHFS VEGQLEFRALLFVPRRAPFD LFENRKKKNNIKLYVRRVFIMDNCE ELIPEYLNFIRGVVDSEDLPLNISR EMLQQSKILKVIRKNLVKKC LELFTELAEDKENYKKFYEQFSKNI KLGIHEDSQNRKKLSELLRYYTSAS GDEMVSLKDYCTRMKENQKH IYYITGETKDQVANSAFVERLRKHG LEVIYMIEPIDEYCVQQLKEFEGKT LVSVTKEGLELPEDEEEKKK QEEKKTKFENLCKIMKDILEKKVEK VVVSNRLVTSPCCIVTSTYGWTANM ERIMKAQALRDNSTMGYMAA KKHLEINPDHSIIETLRQKAEADKN DKSVKDLVILLYETALLSSGFSLED PQTHANRIYRMIKLGLGIDE
  DDPTADDTSAAVTEEMPPLEGDDDT SRMEEVDTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

Gene Information

• Gene Name: HSP90AA1 heat shock protein 90 alpha family class A member 1 [ Homo sapiens (human) ]
• Official Symbol: HSP90AA1
• Synonyms: EL52; HSPN; LAP2; HSP86; HSPC1; HSPCA; Hsp89; Hsp90; LAP-2; HSP89A; HSP90A; HSP90N; Hsp103; HSPCAL1; HSPCAL4; HEL-S-65p
• Gene ID: 3320
• mRNA Refseq: NM_005348.4
• Protein Refseq: NP_005339.3
• MIM: 140571
• UniProt ID: P07900