IL1R1 Protein

IL1R1

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IL1R1

Official Full Name interleukin 1 receptor, type I
Background Tumor Necrosis Factor Receptor Type I (TNFRI); is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-alpha and TNF-beta; (also known as LT-alpha );. The subsequen
Synonyms IL1R1; interleukin 1 receptor, type I; IL1R, IL1RA; interleukin-1 receptor type 1; CD121A; D2S1473; IL-1R-1; IL-1RT1; IL-1RT-1; antigen CD121a; interleukin receptor 1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Homo sapiens (Human)
    • Human
    • Mouse
    • Mus musculus (Mouse)
    • Rat
    • Source :
    • CHO
    • E.coli
    • E.coli expression system
    • HEK293
    • Human Cell
    • Insect Cell
    • Mamanlian cells
    • Mammalian Cell
    • Mammalian cells
    • Spodoptera Frugiperda
    • Tag :
    • Fc
    • His
    • Flag
    • His&Myc
    • His(C-ter)
    • T7
    • His-SUMO & Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL1R1-214H Recombinant Human IL1R1 Protein HEK293 N/A
    Human IL1R1-299H Recombinant Human IL1R1, Fc-tagged HEK293 Fc
    Human IL1R1-3011H Recombinant Human IL1R1, MIgG2a Fc-tagged CHO Fc
    Human IL1R1-3012H Recombinant Human IL1R1, HIgG1 Fc-tagged CHO Fc
    Human IL1R1-627H Recombinant Human IL1R1, Fc-tagged, Biotinylated Human Cell Fc
    Mouse Il1r1-5651M Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged Spodoptera Frugiperda Fc
    Mouse Il1r1-5652M Recombinant Mouse Interleukin 1 Receptor, Type I, His-tagged Mammalian cells His
    Mouse Il1r1-5653M Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged Mammalian cells Fc
    Mouse IL1R1-917M Recombinant Mouse IL1R1 Protein, Fc-tagged HEK293 Fc
    Human IL1R1-14174H Recombinant Human IL1R1, His-tagged E.coli His
    Human IL1R1-1640H Recombinant Human Interleukin 1 Receptor, Type I Mammalian cells N/A
    Human IL1R1-251H Recombinant Human IL1R1 Mammalian Cell His
    Human IL1R1-286H Recombinant Human Interleukin 1 Receptor, Type I, His-tagged E.coli His
    Human IL1R1-368H Recombinant Human IL1R1 Protein, His-tagged Insect Cell His
    Human IL1R1-527H Recombinant Human IL1R1, DDDDK tagged Human Cell His
    Human IL1R1-552H Recombinant Human IL1R1 protein, His-tagged E.coli His
    Human IL1R1-771H Recombinant Human IL1R1, Fc tagged Human Cell Fc
    Human IL1R1-772H Recombinant Human IL1R1, His tagged Human Cell His
    Human IL1R1-879H Recombinant Human IL1R1 protein, His-tagged E.coli His
    Mouse Il1r1-1753M Recombinant Mouse Interleukin 1 Receptor, Type I Mammalian cells N/A
    Mouse Il1r1-5188M Recombinant Mouse Il1r1, His tagged Human Cell His
    Mouse Il1r1-881M Recombinant Mouse Il1r1 protein, His & T7-tagged E.coli His/T7
    Rat Il1r1-4088R Recombinant Rat Il1r1, Fc-His tagged Human Cell Fc/His
    Rat Il1r1-4089R Recombinant Rat Il1r1, His tagged Human Cell His
    Rat Il1r1-882R Recombinant Rat Il1r1 protein, His-tagged E.coli His
    Rat Il1r1-883R Recombinant Rat Il1r1 protein, His-tagged E.coli His
    Rat Il1r1-884R Recombinant Rat Il1r1 protein, His-tagged E.coli His
    Cynomolgus Monkey IL1R1-148C Recombinant Cynomolgus IL1R1, Fc tagged Human Cell His
    Cynomolgus Monkey IL1R1-149C Recombinant Cynomolgus IL1R1, His tagged Human Cell His
    Chicken IL1R1-7034C Recombinant Chicken IL1R1 Mammalian Cell His
    Human IL1R1-1120HCL Recombinant Human IL1R1 cell lysate Human Cell N/A
    Mouse IL1R1-1787MCL Recombinant Mouse IL1R1 cell lysate Human Cell N/A
    Rat IL1R1-1935RCL Recombinant Rat IL1R1 cell lysate Human Cell N/A
    Cynomolgus Monkey IL1R1-945CCL Recombinant Cynomolgus IL1R1 cell lysate Human Cell N/A
    Human IL1R1-164H Recombinant Human IL1R1 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter)
    Human IL1R1-2379H Recombinant Human IL1R1 protein, His-SUMO & Myc-tagged E.coli His-SUMO & Myc
    Human IL1R1-9818HFL Recombinant Full Length Human IL1R1, Flag-tagged Mamanlian cells Flag
    Homo sapiens (Human) RFL30877HF Recombinant Full Length Human Interleukin-1 Receptor Type 1(Il1R1) Protein, His&Myc-Tagged E.coli expression system His&Myc
    Mus musculus (Mouse) RFL7442MF Recombinant Full Length Mouse Interleukin-1 Receptor Type 1(Il1R1) Protein, His-Tagged E.coli expression system His
    Human IL1R1&IL1RAcP-P01H Recombinant Human IL1R1/IL1RAcP, Fc-tagged therapeutic protein Fc

    IL1R1 involved in several pathways and played different roles in them. We selected most pathways IL1R1 participated on our site, such as MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway PLA2G4C; RASGRP3; CACNA2D4; CACNG1; RAF1B; NTF4; CACNB4A; CD14; FGF12A; FGF22
    Cytokine-cytokine receptor interaction VEGFC; IL6R; FLT3LG; THPO; PPBP; OSMR; IFNK; IL1R2; OSTN; GM-CSF
    NF-kappa B signaling pathway TNFRSF13C; BCL2A1A; BCL2A1; ZAP70; BCL10; PTGS2; ICAM1; LTBR; IRAK4; GM10591
    Apoptosis CASP3B; PIK3R3B; PIK3R3; BAX; NFKBIA; PPP3R2; HMGB2; BADB; E2F1; CASP8L1
    Osteoclast differentiation LILRB3; LILRB4; LILRA1; PIK3CG; GRB2; PIK3R3; FCGR2C; PPP3R2; MAPK12; LCP2
    Hematopoietic cell lineage Fcer2a; CD8B; ITGA2; CD37; KIT; CD1D; Kitl; TFRC; IL4R; CD1D2
    Inflammatory mediator regulation of TRP channels CYP2C39; PIK3R5; PPP1CC; CAMK2D; PRKACB; PTGER4; ALOX12E; CYP4A14; ALOX12; PRKACG
    Amoebiasis ACTN1; IFNG; GNAQ; RAB5B; LAMB2; C8A; SERPINB9; TGFB1; GM-CSF; ITGAM
    HTLV-I infection Pdgfa&Pdgfb; RELA; CD40; MAP3K1; HLA-DQA1; WNT5B; HLA-DPA1; NFATC4; MRAS; CRTC1

    IL1R1 has several biochemical functions, for example, interleukin-1 receptor activity, interleukin-1, Type I, activating receptor activity, ionotropic glutamate receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1R1 itself. We selected most functions IL1R1 had, and list some proteins which have the same functions with IL1R1. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-1 receptor activity IL1RAPL2; IL18R1; IL1R1; IL1RL1; IL1R2; IL1RAPL1A; IL1RL2; IL1RAP
    interleukin-1, Type I, activating receptor activity IL1RL2; IL1R1
    ionotropic glutamate receptor binding DLG4; SHANK1; DLG3; FUS; IL1R1; CACNG2; DLG4B; SHANK2; DRD2; ADRB2
    platelet-derived growth factor receptor binding Pdgfa&Pdgfb; PDGFAB; TYMP; IL1R1; PDGFRB; PTEN; ITGA5; PDGFRA; LYN; PDGFA
    protease binding ADAMTSL4; TNFRSF10A; FURIN; THAP5; STIM1; CCBE1; SERPINB6; MBL1; Cstb; SERPINC1
    protein binding DYNAP; ARIH2; KLF2; MIEF1; CRYAA; LDHD; C7orf42; GNB5; FKBP5; OOEP
    signal transducer activity TRIM55; EDNRAA; TAS2R106; RERG; RGS11; MAS1; VALOPA; PTK2AB; OLFR477; EXORH
    transmembrane signaling receptor activity CD300C; LILRB5; FZD3A; SPN; CD72; GP6; HIST2H3C2; OR4C12; NRXN1; ENG

    IL1R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1R1.

    TRAF6; IL1B; IL1RN; TICAM2; IL1RAP; MAP3K14

    Suwara, MI; Green, NJ; et al. IL-1 alpha released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts. MUCOSAL IMMUNOLOGY 7:684-693(2014).
    Britze, A; Palmfeldt, J; et al. 44-plex cytokine profile of cholesteatoma. ACTA OTO-LARYNGOLOGICA 134:41-50(2014).

    IL

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