IL1R1 Protein

IL1R1

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IL1R1

Official Full Name interleukin 1 receptor, type I
Background Tumor Necrosis Factor Receptor Type I (TNFRI); is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-alpha and TNF-beta; (also known as LT-alpha );. The subsequen
Synonyms IL1R1; interleukin 1 receptor, type I; IL1R, IL1RA; interleukin-1 receptor type 1; CD121A; D2S1473; IL-1R-1; IL-1RT1; IL-1RT-1; antigen CD121a; interleukin receptor 1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mamanlian cells
    • Mammalian Cell
    • Mammalian cells
    • Spodoptera Frugiperda
    • Tag :
    • Fc
    • His
    • Flag
    • T7
    • His-SUMO & Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL1R1-14174H Recombinant Human IL1R1, His-tagged E.coli His
    Human IL1R1-1640H Recombinant Human Interleukin 1 Receptor, Type I Mammalian cells N/A
    Human IL1R1-214H Recombinant Human IL1R1 Protein HEK293 N/A
    Human IL1R1-251H Recombinant Human IL1R1 Mammalian Cell His
    Human IL1R1-286H Recombinant Human Interleukin 1 Receptor, Type I, His-tagged E.coli His
    Human IL1R1-299H Recombinant Human IL1R1, Fc-tagged HEK293 Fc
    Human IL1R1-3011H Recombinant Human IL1R1, MIgG2a Fc-tagged CHO Fc
    Human IL1R1-3012H Recombinant Human IL1R1, HIgG1 Fc-tagged CHO Fc
    Human IL1R1-368H Recombinant Human IL1R1 Protein, His-tagged Insect Cell His
    Human IL1R1-527H Recombinant Human IL1R1, DDDDK tagged Human Cell His
    Human IL1R1-552H Recombinant Human IL1R1 protein, His-tagged E.coli His
    Human IL1R1-627H Recombinant Human IL1R1, Fc-tagged, Biotinylated Human Cell Fc
    Human IL1R1-771H Recombinant Human IL1R1, Fc tagged Human Cell Fc
    Human IL1R1-772H Recombinant Human IL1R1, His tagged Human Cell His
    Human IL1R1-879H Recombinant Human IL1R1 protein, His-tagged E.coli His
    Mouse Il1r1-1753M Recombinant Mouse Interleukin 1 Receptor, Type I Mammalian cells N/A
    Mouse Il1r1-5188M Recombinant Mouse Il1r1, His tagged Human Cell His
    Mouse Il1r1-5651M Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged Spodoptera Frugiperda Fc
    Mouse Il1r1-5652M Recombinant Mouse Interleukin 1 Receptor, Type I, His-tagged Mammalian cells His
    Mouse Il1r1-5653M Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged Mammalian cells Fc
    Mouse Il1r1-881M Recombinant Mouse Il1r1 protein, His & T7-tagged E.coli His/T7
    Mouse IL1R1-917M Recombinant Mouse IL1R1 Protein, Fc-tagged HEK293 Fc
    Rat Il1r1-4088R Recombinant Rat Il1r1, Fc-His tagged Human Cell Fc/His
    Rat Il1r1-4089R Recombinant Rat Il1r1, His tagged Human Cell His
    Rat Il1r1-882R Recombinant Rat Il1r1 protein, His-tagged E.coli His
    Rat Il1r1-883R Recombinant Rat Il1r1 protein, His-tagged E.coli His
    Rat Il1r1-884R Recombinant Rat Il1r1 protein, His-tagged E.coli His
    Cynomolgus Monkey IL1R1-148C Recombinant Cynomolgus IL1R1, Fc tagged Human Cell His
    Cynomolgus Monkey IL1R1-149C Recombinant Cynomolgus IL1R1, His tagged Human Cell His
    Chicken IL1R1-7034C Recombinant Chicken IL1R1 Mammalian Cell His
    Human IL1R1-1120HCL Recombinant Human IL1R1 cell lysate Human Cell N/A
    Mouse IL1R1-1787MCL Recombinant Mouse IL1R1 cell lysate Human Cell N/A
    Rat IL1R1-1935RCL Recombinant Rat IL1R1 cell lysate Human Cell N/A
    Cynomolgus Monkey IL1R1-945CCL Recombinant Cynomolgus IL1R1 cell lysate Human Cell N/A
    Human IL1R1-2379H Recombinant Human IL1R1 protein, His-SUMO & Myc-tagged E.coli His-SUMO & Myc
    Human IL1R1-9818HFL Recombinant Full Length Human IL1R1, Flag-tagged Mamanlian cells Flag
    Human IL1R1&IL1RAcP-P01H Recombinant Human IL1R1/IL1RAcP, Fc-tagged therapeutic protein Fc

    IL1R1 involved in several pathways and played different roles in them. We selected most pathways IL1R1 participated on our site, such as MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway RAC3A; FGF14; MRAS; MAPKAPK5; FLNA; RAC1A; MAP3K14; IL1B; CACNA1B; FOS
    Cytokine-cytokine receptor interaction CCL13; PPBP; Ccl12; Il6ra; CCL4; PDGFC; CCR6A; TNFRSF14; IL4; PRP2
    NF-kappa B signaling pathway GADD45B; BCL2; RIPK1; GM10591; ERC1; TAB2; LTB; MAP3K14; TRAF5; RELA
    Apoptosis PPP3CCA; CASP10; IKBKB; MYD88; IRF1B; DERL3; FADD; CASP4; RNF8; CASP8
    Osteoclast differentiation TNFRSF1A; CAMK4; LILRA5; TYK2; CYBA; NFKB1; FCGR2A; TRAF2; MAP3K7; FCGR1
    Hematopoietic cell lineage IL11; HLA-DRA; CD37; ITGAM; IL7; CD1E, B2M; IL6; GM-CSF; CD9; TFRC
    Inflammatory mediator regulation of TRP channels MAPK8; MAPK13; HRH1; ASIC3; IL1R1; MAP2K3; PRKCQ; PPP1CB; CYP2C38; PIK3R1
    Amoebiasis SERPINB1; ACTN4; RAB5C; RAB5B; IL1B; TGFB3; COL5A1; COL1A1; ADCY1; ARG1
    HTLV-I infection HLA-G; GSK3B; WNT7A; WNT11; PIK3CB; GM-CSF; HLA-DQA1; ANAPC4; PCNA; IKBKB

    IL1R1 has several biochemical functions, for example, interleukin-1 receptor activity, interleukin-1, Type I, activating receptor activity, ionotropic glutamate receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1R1 itself. We selected most functions IL1R1 had, and list some proteins which have the same functions with IL1R1. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-1 receptor activity IL1RL1; IL1R1; IL1RL2; IL1R2; IL1RAPL2; IL18R1; IL1RAP; IL1RAPL1A
    interleukin-1, Type I, activating receptor activity IL1RL2; IL1R1
    ionotropic glutamate receptor binding SHANK2; DLG2; RAB4A; GNAS; FLOT2; DLG1L; DLG4; DLG4B; SHANK3; SHANK1
    platelet-derived growth factor receptor binding ITGA5; PDGFC; PTEN; TYMP; Pdgfa&Pdgfb; PDGFRB; FIGF; ITGB3; IL1R1; PTPRJ
    protease binding SEMG2; BCL10; ADRM1; FADD; INS; IL1R1; PANX1; RNF139; NFRKB; CAST
    protein binding C19orf57; HJURP; ZG16; G3BP2; VARS; PCGF2; BTC; HPGDS; KCNE1L; TFAP4
    signal transducer activity OR103-4; APLNRA; VMN1R46; C18orf32; TAS2R137; CXCR2; PDCD1; OPRD1B; OPN1LW2; OLFR469
    transmembrane signaling receptor activity GIPR; GHRHRA; LILRB3; RYK; SLC22A17; LILRB5; TLR3; SPN; FZD8B; GHRHR2

    IL1R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1R1.

    TRAF6; IL1B; IL1RN; TICAM2; IL1RAP; MAP3K14

    Suwara, MI; Green, NJ; et al. IL-1 alpha released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts. MUCOSAL IMMUNOLOGY 7:684-693(2014).
    Britze, A; Palmfeldt, J; et al. 44-plex cytokine profile of cholesteatoma. ACTA OTO-LARYNGOLOGICA 134:41-50(2014).

    IL

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