IL1R1 Protein

IL1R1

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IL1R1

Official Full Name interleukin 1 receptor, type I
Background Tumor Necrosis Factor Receptor Type I (TNFRI); is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-alpha and TNF-beta; (also known as LT-alpha );. The subsequen
Synonyms IL1R1; interleukin 1 receptor, type I; IL1R, IL1RA; interleukin-1 receptor type 1; CD121A; D2S1473; IL-1R-1; IL-1RT1; IL-1RT-1; antigen CD121a; interleukin receptor 1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Homo sapiens (Human)
    • Human
    • Mouse
    • Mus musculus (Mouse)
    • Rat
    • Source :
    • CHO
    • E.coli
    • E.coli expression system
    • HEK293
    • Human Cell
    • Insect Cell
    • Mamanlian cells
    • Mammalian Cell
    • Mammalian cells
    • Spodoptera Frugiperda
    • Tag :
    • DDDDK
    • Fc
    • His
    • Flag
    • His&Myc
    • His(C-ter)
    • T7
    • His-SUMO & Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL1R1-214H Active Recombinant Human IL1R1 Protein HEK293 N/A Inquiry
    Human IL1R1-299H Active Recombinant Human IL1R1, Fc-tagged HEK293 Fc Inquiry
    Human IL1R1-3011H Active Recombinant Human IL1R1, MIgG2a Fc-tagged CHO Fc Inquiry
    Human IL1R1-3012H Active Recombinant Human IL1R1, HIgG1 Fc-tagged CHO Fc Inquiry
    Human IL1R1-627H Active Recombinant Human IL1R1, Fc-tagged, Biotinylated Human Cell Fc Inquiry
    Mouse Il1r1-5651M Active Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged Spodoptera Frugiperda Fc Inquiry
    Mouse Il1r1-5652M Active Recombinant Mouse Interleukin 1 Receptor, Type I, His-tagged Mammalian cells His Inquiry
    Mouse Il1r1-5653M Active Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged Mammalian cells Fc Inquiry
    Mouse IL1R1-917M Active Recombinant Mouse IL1R1 Protein, Fc-tagged HEK293 Fc Inquiry
    Human IL1R1-14174H Recombinant Human IL1R1, His-tagged E.coli His Inquiry
    Human IL1R1-1640H Recombinant Human Interleukin 1 Receptor, Type I Mammalian cells N/A Inquiry
    Human IL1R1-251H Recombinant Human IL1R1 Mammalian Cell His Inquiry
    Human IL1R1-286H Recombinant Human Interleukin 1 Receptor, Type I, His-tagged E.coli His Inquiry
    Human IL1R1-368H Recombinant Human IL1R1 Protein, His-tagged Insect Cell His Inquiry
    Human IL1R1-527H Recombinant Human IL1R1, DDDDK-tagged HEK293 DDDDK Inquiry
    Human IL1R1-552H Recombinant Human IL1R1 protein, His-tagged E.coli His Inquiry
    Human IL1R1-771H Recombinant Human IL1R1, Fc tagged Human Cell Fc Inquiry
    Human IL1R1-772H Recombinant Human IL1R1, His tagged Human Cell His Inquiry
    Human IL1R1-879H Recombinant Human IL1R1 protein, His-tagged E.coli His Inquiry
    Mouse Il1r1-1753M Recombinant Mouse Interleukin 1 Receptor, Type I Mammalian cells N/A Inquiry
    Mouse Il1r1-5188M Recombinant Mouse Il1r1, His tagged Human Cell His Inquiry
    Mouse Il1r1-881M Recombinant Mouse Il1r1 protein, His & T7-tagged E.coli His/T7 Inquiry
    Rat Il1r1-4088R Recombinant Rat Il1r1, Fc-His tagged Human Cell Fc/His Inquiry
    Rat Il1r1-4089R Recombinant Rat Il1r1, His tagged Human Cell His Inquiry
    Rat Il1r1-882R Recombinant Rat Il1r1 protein, His-tagged E.coli His Inquiry
    Rat Il1r1-883R Recombinant Rat Il1r1 protein, His-tagged E.coli His Inquiry
    Rat Il1r1-884R Recombinant Rat Il1r1 protein, His-tagged E.coli His Inquiry
    Cynomolgus Monkey IL1R1-148C Recombinant Cynomolgus IL1R1, Fc tagged Human Cell His Inquiry
    Cynomolgus Monkey IL1R1-149C Recombinant Cynomolgus IL1R1, His tagged Human Cell His Inquiry
    Chicken IL1R1-7034C Recombinant Chicken IL1R1 Mammalian Cell His Inquiry
    Human IL1R1-1120HCL Recombinant Human IL1R1 cell lysate Human Cell N/A Inquiry
    Mouse IL1R1-1787MCL Recombinant Mouse IL1R1 cell lysate Human Cell N/A Inquiry
    Rat IL1R1-1935RCL Recombinant Rat IL1R1 cell lysate Human Cell N/A Inquiry
    Cynomolgus Monkey IL1R1-945CCL Recombinant Cynomolgus IL1R1 cell lysate Human Cell N/A Inquiry
    Human IL1R1-164H Recombinant Human IL1R1 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Inquiry
    Human IL1R1-2379H Recombinant Human IL1R1 protein, His-SUMO & Myc-tagged E.coli His-SUMO & Myc Inquiry
    Human IL1R1-9818HFL Recombinant Full Length Human IL1R1, Flag-tagged Mamanlian cells Flag Inquiry
    Homo sapiens (Human) RFL30877HF Recombinant Full Length Human Interleukin-1 Receptor Type 1(Il1R1) Protein, His&Myc-Tagged E.coli expression system His&Myc Inquiry
    Mus musculus (Mouse) RFL7442MF Recombinant Full Length Mouse Interleukin-1 Receptor Type 1(Il1R1) Protein, His-Tagged E.coli expression system His Inquiry
    Human IL1R1&IL1RAcP-P01H Recombinant Human IL1R1/IL1RAcP, Fc-tagged therapeutic protein Fc Inquiry

    IL1R1 involved in several pathways and played different roles in them. We selected most pathways IL1R1 participated on our site, such as MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway Fasl; CACNA1SA; PRKCBB; MAPK8A; PRKACAB; FGF17; CACNG4; RAC3; TMEM37; HSPA8
    Cytokine-cytokine receptor interaction CX3CL1; IL17B; BMPR2A; CCL25; EGFRA; LTBR; Ifna15; CXCL6; CXCR4A; IFNE
    NF-kappa B signaling pathway Ccl21a; LTBR; ICAM1; PRKCB; IKBKG; GM10591; PRKCQ; IL1B; CARD11; BCL2A1A
    Apoptosis NMT1; IL1R1; HMGB2A; CAPN1A; XIAP; SPNA2; TRADD; CASP2; DSG1; IRF4
    Osteoclast differentiation IFNB1; IFNGR2; FOS; PPP3R1; RELA; FCGR3A; IKBKB; TGFBR1; SOCS1; FCGR2B
    Hematopoietic cell lineage GP5; CSF1R; HLA-DRB1; IL11RA; IL4; CD1d1; CD3D; ITGA6; IL9R; CD1E
    Inflammatory mediator regulation of TRP channels CAMK2G; BDKRB2; ACCN4; HRH1; HTR2B; CAMK2A; SRC; PLA2G4D; ASIC4; CYP2J6
    Amoebiasis IL6; NOS2; AASS; CD14; GNAL; C8A; SERPINB10; SERPINB6; PRKACB; RAB5C
    HTLV-I infection TBPL2; PIK3R5; SFPI1; H2-AA; POLD1; HLA-DRB3; ATF1; WNT3A; TGFBR2; IKBKB

    IL1R1 has several biochemical functions, for example, interleukin-1 receptor activity, interleukin-1, Type I, activating receptor activity, ionotropic glutamate receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1R1 itself. We selected most functions IL1R1 had, and list some proteins which have the same functions with IL1R1. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-1 receptor activity IL1R2; IL1RL2; IL1RL1; IL1R1; IL1RAP; IL18R1; IL1RAPL2; IL1RAPL1A
    interleukin-1, Type I, activating receptor activity IL1RL2; IL1R1
    ionotropic glutamate receptor binding DLG4B; DLG4; FLOT2; DRD2; SHANK1; SHANK3; ADRB2; IL1R1; FUS; GNAS
    platelet-derived growth factor receptor binding IL1R1; ITGB3; PDGFA; Pdgfa&Pdgfb; PDGFRB; VEGFA; PDGFRA; ITGA5; FIGF; PDGFD
    protease binding STIM1; ALPI; SERPINB4; TIMP1; ANXA2; CRADD; TRP53; FAP; Serpina1c; TNFAIP3
    protein binding WIPF1; SPEF2; INHA; CDC37L1; FRK; LNX1; IL28RA; GORASP2; SOX13; CUTC
    signal transducer activity TAAR15; TAS2R116; TMED4; GRM2A; OLFCG1; RERG; GNG13; OLFR50; GNA15.4; GRM6B
    transmembrane signaling receptor activity LGR5; MPL; TLR2; CELSR1; FZD3B; CD3D; GHRHRA; THBD; CD5; P2RX5

    IL1R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1R1.

    TRAF6; IL1B; IL1RN; TICAM2; IL1RAP; MAP3K14

    Suwara, MI; Green, NJ; et al. IL-1 alpha released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts. MUCOSAL IMMUNOLOGY 7:684-693(2014).
    Britze, A; Palmfeldt, J; et al. 44-plex cytokine profile of cholesteatoma. ACTA OTO-LARYNGOLOGICA 134:41-50(2014).

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