Official Full Name | interleukin 1 receptor, type I |
Background | Tumor Necrosis Factor Receptor Type I (TNFRI); is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-alpha and TNF-beta; (also known as LT-alpha );. The subsequen |
Synonyms | IL1R1; interleukin 1 receptor, type I; IL1R, IL1RA; interleukin-1 receptor type 1; CD121A; D2S1473; IL-1R-1; IL-1RT1; IL-1RT-1; antigen CD121a; interleukin receptor 1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family |
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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IL1R1 involved in several pathways and played different roles in them. We selected most pathways IL1R1 participated on our site, such as MAPK signaling pathway, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL1R1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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MAPK signaling pathway | Fasl; CACNA1SA; PRKCBB; MAPK8A; PRKACAB; FGF17; CACNG4; RAC3; TMEM37; HSPA8 |
Cytokine-cytokine receptor interaction | CX3CL1; IL17B; BMPR2A; CCL25; EGFRA; LTBR; Ifna15; CXCL6; CXCR4A; IFNE |
NF-kappa B signaling pathway | Ccl21a; LTBR; ICAM1; PRKCB; IKBKG; GM10591; PRKCQ; IL1B; CARD11; BCL2A1A |
Apoptosis | NMT1; IL1R1; HMGB2A; CAPN1A; XIAP; SPNA2; TRADD; CASP2; DSG1; IRF4 |
Osteoclast differentiation | IFNB1; IFNGR2; FOS; PPP3R1; RELA; FCGR3A; IKBKB; TGFBR1; SOCS1; FCGR2B |
Hematopoietic cell lineage | GP5; CSF1R; HLA-DRB1; IL11RA; IL4; CD1d1; CD3D; ITGA6; IL9R; CD1E |
Inflammatory mediator regulation of TRP channels | CAMK2G; BDKRB2; ACCN4; HRH1; HTR2B; CAMK2A; SRC; PLA2G4D; ASIC4; CYP2J6 |
Amoebiasis | IL6; NOS2; AASS; CD14; GNAL; C8A; SERPINB10; SERPINB6; PRKACB; RAB5C |
HTLV-I infection | TBPL2; PIK3R5; SFPI1; H2-AA; POLD1; HLA-DRB3; ATF1; WNT3A; TGFBR2; IKBKB |
IL1R1 has several biochemical functions, for example, interleukin-1 receptor activity, interleukin-1, Type I, activating receptor activity, ionotropic glutamate receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL1R1 itself. We selected most functions IL1R1 had, and list some proteins which have the same functions with IL1R1. You can find most of the proteins on our site.
Function | Related Protein |
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interleukin-1 receptor activity | IL1R2; IL1RL2; IL1RL1; IL1R1; IL1RAP; IL18R1; IL1RAPL2; IL1RAPL1A |
interleukin-1, Type I, activating receptor activity | IL1RL2; IL1R1 |
ionotropic glutamate receptor binding | DLG4B; DLG4; FLOT2; DRD2; SHANK1; SHANK3; ADRB2; IL1R1; FUS; GNAS |
platelet-derived growth factor receptor binding | IL1R1; ITGB3; PDGFA; Pdgfa&Pdgfb; PDGFRB; VEGFA; PDGFRA; ITGA5; FIGF; PDGFD |
protease binding | STIM1; ALPI; SERPINB4; TIMP1; ANXA2; CRADD; TRP53; FAP; Serpina1c; TNFAIP3 |
protein binding | WIPF1; SPEF2; INHA; CDC37L1; FRK; LNX1; IL28RA; GORASP2; SOX13; CUTC |
signal transducer activity | TAAR15; TAS2R116; TMED4; GRM2A; OLFCG1; RERG; GNG13; OLFR50; GNA15.4; GRM6B |
transmembrane signaling receptor activity | LGR5; MPL; TLR2; CELSR1; FZD3B; CD3D; GHRHRA; THBD; CD5; P2RX5 |
IL1R1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL1R1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL1R1.
TRAF6; IL1B; IL1RN; TICAM2; IL1RAP; MAP3K14
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