Active Recombinant Mouse Interleukin 1 Receptor, Type I, Fc-tagged
Cat.No. : | Il1r1-5653M |
Product Overview : | RecombinantMouse Il1r1 protein was expressed in Murine myeloma celllinewith the Fc part of Human IgG1 Pro100-Lys330 (C-terminus) and MouseIl1r1 Leu20-Lys338 (N-terminus). |
- Specification
- Gene Information
- Related Products
Cat. No. : | Il1r1-5653M |
Description : | Il1r1 isan 80 kDa transmembrane protein that is expressed predominantly by T cells,fibroblasts, and endothelialcells. IL-1 receptor Type II is a 68 kDatransmembrane protein found on B lymphocytes, neutrophils, monocytes, largegranular leukocytes and endothelial cells. Both receptors are members of theimmunoglobulin superfamily and show approximately 28% sequence identity intheir extracellular domains. The two receptor types do not heterodimerize intoa receptor complex. Mouse Il1r1 shares 63% amino acid sequence homology withhuman Il1r1 in their extracellular domains. |
Source : | Mammalian cells |
Form : | Lyophilizedfrom a 0.2 um filtered solution in PBS. |
N-terminalSequence : | Leu20 |
MolecularWeight : | 63.8 kDa (monomer) |
Activity : | Measuredby its ability to inhibit IL-1α-dependent proliferation in D10.G4.1 mouse helperT cells. Approximately 0.005-0.015 μg/mL of IL-1 sRI/Fc will inhibit 50% ofthe biological response due to 50 pg/mL of rmIL-1a. |
Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
SDS-PAGE : | 95-110kDa, reducing conditions. |
Purity : | >90%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | 100 μg/mLin sterile PBS |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution. |
Gene Name : | Il1r1 interleukin 1 receptor,type I [ Mus musculus ] |
Official Symbol : | Il1r1 |
Synonyms : | Il1r1; interleukin 1receptor, type I; IL-iR; CD121a;CD121b; Il1r-1; interleukin-1 receptor type 1; p80; IL-1R-1; IL-1RT1;IL-1RT-1; IL-1R-alpha; IL-1 receptor alpha chain; interleukin-1 receptoralpha; interleukin-1 receptor type I; CD121 antigen-like family member A |
Gene ID : | 16177 |
mRNA Refseq : | NM_001123382 |
Protein Refseq : | NP_001116854 |
UniProt ID : | Q4FK69 |
Chromosome Location : | 1 |
Pathway : | Amoebiasis;Apoptosis; Cytokine-cytokine receptor interaction; HTLV-I infection;Hematopoietic cell lineage; Hypertrophy Model; IL-1 Signaling Pathway; MAPKsignaling pathway; Osteoclast differentiation |
Function : | interleukin-1receptor activity; interleukin-1, Type I, activating receptor activity;ionotropic glutamate receptor binding; platelet-derived growth factorreceptor binding; protease binding; protein binding; receptor activity;signal transducer activity; transmembrane signaling receptor activity |
Products Types
◆ Recombinant Protein | ||
IL1R1-064H | Recombinant Human IL1R1 Protein, C-His-tagged | +Inquiry |
IL1R1-02H | Active Recombinant Human IL1R1 Protein (19-328aa), C-His-tagged | +Inquiry |
IL1R1-3147H | Recombinant Human IL1R1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Il1r1-10581M | Recombinant Mouse Il1r1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL1R1-164H | Recombinant Human IL1R1 Protein (ECD), His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL1R1-1935RCL | Recombinant Rat IL1R1 cell lysate | +Inquiry |
IL1R1-1120HCL | Recombinant Human IL1R1 cell lysate | +Inquiry |
IL1R1-945CCL | Recombinant Cynomolgus IL1R1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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