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  • Official Full Name

    interleukin 24

  • Overview

    This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
  • Synonyms

    IL24; interleukin 24; ST16; interleukin-24; C49A; FISP; IL 4 induced secreted protein; IL 24; IL10B; mda 7; melanoma differentiation association protein 7; Mob 5; suppression of tumorigenicity 16 (melanoma differentiation); melanocyte-associated Mda-7; IL;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • CHO
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Human Cells
  • Mammalian Cell
  • Mammalian cells
  • S.cerevisiae
  • Wheat Germ
  • C
  • His
  • Fc
  • GST
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • His|GST
  • MIgG1 Fc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL24-584H Active Recombinant Human IL24, MIgG2a Fc-tagged CHO Fc
Human IL24-586H Active Recombinant Human IL24, HIgG1 Fc-tagged CHO Fc
Human IL24-585H Active Recombinant Human IL24, HIgG1 Fc-tagged, mutant CHO Fc
Human IL24-14189H Recombinant Human IL24, GST-tagged E.coli GST 1-207a.a.
Human IL24-589H Recombinant Human IL24 protein, His-tagged E.coli His Gly51~Leu206
Human IL24-276H Recombinant Human Interleukin 24 S.cerevisiae N/A
Human IL24-380H Active Recombinant Human IL24 protein, His-tagged HEK293 His Met1-Leu207
Human IL24-934H Recombinant Human IL24 Protein, His-tagged CHO His
Human IL24-1922HCL Recombinant Human IL24 cell lysate Human Cell N/A
Human IL24-151H Recombinant Human IL24 Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human IL24-553H Recombinant Human IL24 Protein (Met1-Leu207), MIgG1 Fc-tagged HEK293 MIgG1 Fc Met1-Leu207
Human IL24-5211H Recombinant Human IL24 Protein, GST-tagged Wheat Germ GST
Human IL24-180H Recombinant Active Human IL24 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human IL24-1314H Active Recombinant Human IL24 protein, His-tagged HEK293 His Gln52-Leu206
Human IL24-2978H Recombinant Human IL24 protein, His-tagged E.coli His 53-207 aa
Human IL24-2875H Recombinant Human IL24 Protein (Gln52-Leu206), N-His tagged E.coli N-His Gln52-Leu206
Human IL24-2876H Recombinant Human IL24 Protein (Gln52-Leu260), His tagged E.coli His Gln52-Leu260
Human IL24-510H Recombinant Human IL24 Protein 163
Human IL24-3952H Recombinant Human IL24 Protein (Met1-Leu207), C-His tagged Mammalian cells C-His Met1-Leu207
Human IL24-10H Active Recombinant Human IL24 Protein (Gln52-Leu206), C-His tagged, Animal-free, Carrier-free E.coli C-His Gln52-Leu206
Human IL24-1925H Recombinant Human IL24 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse Il24-796M Active Recombinant Mouse Il24 Mammalian cells N/A Gln66-Leu220
Mouse Il24-01M Active Recombinant Mouse Il24 Protein, His-Tagged E.coli His
Mouse IL24-8158M Recombinant Mouse IL24 Protein Mammalian Cell His
Mouse Il24-10583M Recombinant Mouse Il24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Il24-3517M Recombinant Mouse Il24 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Il24-320M Active Recombinant Mouse Il24 Protein (Gln27-Leu181), C-His tagged, Animal-free, Carrier-free E.coli C-His Gln27-Leu181
Mouse Il24-181M Recombinant Active Mouse IL24 Protein, His-tagged(C-ter) E.coli His(C-ter)
Mouse Il24-10583M-B Recombinant Mouse Il24 Protein Pre-coupled Magnetic Beads HEK293
Rat Il24-30R Recombinant Rat Il24 protein, His-tagged E.coli His Gln29~Leu183
Rat IL24-3042R Recombinant Rat IL24 Protein Mammalian Cell His
Rat Il24-194R Recombinant Rat Il24 Protein, His/GST-tagged E.coli His/GST Gln29~Leu183
Rat IL24-2697R-B Recombinant Rat IL24 Protein Pre-coupled Magnetic Beads HEK293
Rat IL24-2697R Recombinant Rat IL24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IL24 Related Articles
  • IL24 Related Gene Family
  • IL24 Related Research Area

IL24 involved in several pathways and played different roles in them. We selected most pathways IL24 participated on our site, such as Cytokine-cytokine receptor interaction, IL23-mediated signaling events, Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionGM13306;RELT;ACVR2B;Il2;CRFB2;TNFRSF8;CCL6;CCL28;IFNA21
IL23-mediated signaling eventsIL24;IL17F;IL23R
Jak-STAT signaling pathwayTP-1;Il23a; Il12b;GRB2;IL9;IL11RA;IL7R;CISHB;PTPN2B;TSLP
Senescence and AutophagyMAP1LC3C;IFI16;CREG1;ING1;IGFBP7;RSL1D1;IL24;AMBRA1;SLC39A3

IL24 has several biochemical functions, for example, cytokine activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL24 itself. We selected most functions IL24 had, and list some proteins which have the same functions with IL24. You can find most of the proteins on our site.

Function Related Protein
cytokine activityGM13285;IL32;ILTIFB;TNFSF14;IL17A/F2;IL13;CSF3;THPO;CMTM6
protein bindingKHDC3;EVLA;RPUSD3;UCHL3;HACE1;C21orf2;ARFGAP1;TPR;ZNF433

IL24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL24 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL24.


Xu, J; Mo, YW; et al. Conditionally replicative adenovirus-based mda-7/IL-24 expression enhances sensitivity of colon cancer cells to 5-fluorouracil and doxorubicin. JOURNAL OF GASTROENTEROLOGY 48:203-213(2013).
Bakshi, S; Zhang, X; et al. Transcriptome analyses in normal prostate epithelial cells exposed to low-dose cadmium: Oncogenic and immunomodulations involving the action of tumor necrosis factor. ENVIRONMENTAL HEALTH PERSPECTIVES 116:769-776(2008).
  • Q&As
  • Reviews

Q&As (6)

Ask a question
Are there side effects of Il24? 12/31/2022

The current study shows that the side effects of Il24 are relatively small, and mainly reflected in local reactions, allergic reactions, etc.

Is Il24 safer and more effective than other treatments? 05/22/2022

The safety and efficacy of Il24 need to be validated through more clinical studies, and the safety and efficacy of specific applications need to be evaluated based on individual patient differences.

Which molecules does Il24 interact with? 07/18/2021

Il24 interacts with IL20 receptor complex, IL22 protein, etc.

How does Il24 interfere with the immune system? 08/31/2020

It mainly regulates or interferes with the relevant processes of the immune system by inhibiting some mediators secreted by immune cells, such as cytokines and chemokines.

What are the advantages of Il24 application? 02/27/2020

Il24 has good biological activity, stability and repeatability, and can be large-scale produced by genetic engineering technology, which has potential drug development and application prospects.

Can recombinant Il24 be used to treat tumors? 09/29/2019

Yes, Il24 has been shown to treat many types of solid tumors, including brain glioma, melanoma, lung cancer, prostate cancer, and more.

Customer Reviews (3)

Write a review

    Very high quality, very reliable.


      Very pure, safe to use.


        High stability, can be stored for a long time.

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