Active Recombinant Mouse Il24

• Cat.No.: Il24-796M
• Product Overview: Recombinant Mouse Il24 (Accession # NP_444325) Gln66-Leu220, fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Predicted N Terminal: Gln66 predicted: No results obtained, sequencing might be blocked
• Form: Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
• Bio-activity: Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL-20 R alpha and human IL-20 R beta.The ED50 for this effect is typically 0.07-0.35 ng/mL.
• Molecular Mass: Recombinant Mouse Il24 has a calculated MW of 18 kDa (monomer). In SDS-PAGE migrates as 19-23 kDa, reducing conditions.
• Protein length: Gln66-Leu220
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Il24 interleukin 24 [ Mus musculus ]
• Official Symbol: Il24
• Synonyms: IL24; interleukin 24; interleukin-24; IL-24; th2-specific cytokine FISP; IL-4-induced secreted protein; melanoma differentiation-associated gene 7 protein; FISP; Mda7; St16; Mda-7
• Gene ID: 93672
• mRNA Refseq: NM_053095
• Protein Refseq: NP_444325

Reviews

07/07/2022

Very high quality, very reliable.

02/03/2021

Very pure, safe to use.

11/17/2019

High stability, can be stored for a long time.

Q&As

Are there side effects of Il24?

The current study shows that the side effects of Il24 are relatively small, and mainly reflected in local reactions, allergic reactions, etc.

Is Il24 safer and more effective than other treatments?

The safety and efficacy of Il24 need to be validated through more clinical studies, and the safety and efficacy of specific applications need to be evaluated based on individual patient differences.

Which molecules does Il24 interact with?

Il24 interacts with IL20 receptor complex, IL22 protein, etc.

How does Il24 interfere with the immune system?

It mainly regulates or interferes with the relevant processes of the immune system by inhibiting some mediators secreted by immune cells, such as cytokines and chemokines.

What are the advantages of Il24 application?

Il24 has good biological activity, stability and repeatability, and can be large-scale produced by genetic engineering technology, which has potential drug development and application prospects.

Can recombinant Il24 be used to treat tumors?

Yes, Il24 has been shown to treat many types of solid tumors, including brain glioma, melanoma, lung cancer, prostate cancer, and more.