Active Recombinant Human IL24 Protein (Gln52-Leu206), C-His tagged, Animal-free, Carrier-free
Cat.No. : | IL24-10H |
Product Overview : | Recombinant Human IL24 Protein (Gln52-Leu206) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
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Description : | Interleukin 24 (IL-24) predicts a molecular mass of 18.2 kDa, is a cytokine belonging to the IL-10 family of cytokines that signals through IL-20R1 /IL-20R2 and IL-22R1 /IL-20R2. Its normal physiological role relates to wound healing, protection against diseases caused by bacteria. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to chemoattract BaF3 cells transfected with human IL-20R alpha and IL-20R beta. The ED50 for this effect is < 120 pg/mL. |
Molecular Mass : | The protein has a calculated MW of 19.10 kDa. The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Gln52-Leu206 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >95% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | IL24 interleukin 24 [ Homo sapiens (human) ] |
Official Symbol : | IL24 |
Synonyms : | IL24; interleukin 24; ST16; interleukin-24; C49A; FISP; IL 4 induced secreted protein; IL 24; IL10B; mda 7; melanoma differentiation association protein 7; Mob 5; suppression of tumorigenicity 16 (melanoma differentiation); melanocyte-associated Mda-7; IL-4-induced secreted protein; melanoma differentiation-associated gene 7 protein; MDA7; MOB5; |
Gene ID : | 11009 |
mRNA Refseq : | NM_001185156 |
Protein Refseq : | NP_001172085 |
MIM : | 604136 |
UniProt ID : | Q13007 |
Products Types
◆ Recombinant Protein | ||
IL24-1925H | Recombinant Human IL24 Protein, MYC/DDK-tagged | +Inquiry |
IL24-180H | Recombinant Active Human IL24 Protein, His-tagged(C-ter) | +Inquiry |
Il24-10583M | Recombinant Mouse Il24 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL24-553H | Recombinant Human IL24 Protein (Met1-Leu207), MIgG1 Fc-tagged | +Inquiry |
IL24-2697R | Recombinant Rat IL24 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL24-1922HCL | Recombinant Human IL24 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewVery high quality, very reliable.
Very pure, safe to use.
High stability, can be stored for a long time.
Q&As (6)
Ask a questionThe current study shows that the side effects of Il24 are relatively small, and mainly reflected in local reactions, allergic reactions, etc.
The safety and efficacy of Il24 need to be validated through more clinical studies, and the safety and efficacy of specific applications need to be evaluated based on individual patient differences.
Il24 interacts with IL20 receptor complex, IL22 protein, etc.
It mainly regulates or interferes with the relevant processes of the immune system by inhibiting some mediators secreted by immune cells, such as cytokines and chemokines.
Il24 has good biological activity, stability and repeatability, and can be large-scale produced by genetic engineering technology, which has potential drug development and application prospects.
Yes, Il24 has been shown to treat many types of solid tumors, including brain glioma, melanoma, lung cancer, prostate cancer, and more.
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