RETN
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Official Full Name
resistin
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Overview
This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010] -
Synonyms
RETN; resistin; ADSF; RSTN; XCP1; FIZZ3; RETN1; resistin delta2; found in inflammatory zone 3; cysteine-rich secreted protein FIZZ3; adipose tissue-specific secretory factor; cysteine-rich secreted protein A12-alpha-like 2; c/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Cell & Tissue Lysates
- Bovine
- Cattle
- Human
- Mouse
- Pig
- Rat
- Rhesus Macaque
- E. coli
- E.coli
- HEK293
- HEK293F
- HEK293T
- Human Cell
- Mamanlian cells
- Mammalian Cell
- Mammalian cells
- C
- Fc
- His
- Flag
- His (Fc)
- Avi
- His|Fc
- His|GST
- His|T7
- SUMO
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- RETN Related Articles
- RETN Related Research Area
RETN involved in several pathways and played different roles in them. We selected most pathways RETN participated on our site, such as Adipogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with RETN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adipogenesis | SPOCK1;EGR2;GATA2A;MIXL1;MEF2B;KCNA3;SMAD3B;PLIN2;CEBPD |
RETN has several biochemical functions, for example, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RETN itself. We selected most functions RETN had, and list some proteins which have the same functions with RETN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | RLN3;EPO;LEP;EDN3;ADM2A;HAMP;PYYA;PRL2C3;IGF2A |
RETN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RETN here. Most of them are supplied by our site. Hope this information will be useful for your research of RETN.
- Q&As
- Reviews
Q&As (6)
Ask a questionExpression level of RETN is associated with the development of insulin resistance. High levels of RETN can reduce insulin sensitivity, leading to decreased glycemic control, which promotes the development of insulin resistance.
Studies have shown that regulating the expression level of RETN can influence the development and treatment effect of diabetes and cardiovascular disease. For example, certain drugs can improve insulin sensitivity and control blood sugar levels by inhibiting the expression level of RETN.
Diabetes and cardiovascular disease can be predicted and diagnosed by measuring the expression level of RETN. For example, high levels of RETN may indicate a higher risk of disease and more severe disease conditions.
Mutations and expression levels of the RETN gene can be detected to aid in diagnosing disease and assessing prognosis. For example, certain mutations may predict a higher risk and a worse prognosis.
Mutations or abnormal expression of RETN may be associated with a variety of diseases. For example, certain mutations can lead to abnormally elevated levels of their expression, increasing the risk of diabetes, cardiovascular disease, etc.
RETN has some association with other biomarkers. For example, in obesity and cardiovascular disease, the expression level of RETN can be used to assess the prognosis and therapeutic effect of the disease together with biomarkers such as adiponectin and leptin.
Customer Reviews (3)
Write a reviewCatalytic activity of RETN is excellent, no matter what the environment can maintain stable catalytic performance, its reliability is reliable.
The quality of RETN they produce is guaranteed, and we can buy it with confidence.
The stability of RETN is too strong to ignore, and it remains admirably stable after long storage.
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