50 donor Pooled Human Liver Microsomes

• Cat.No.: Liver Microsomes-001H
• Product Overview: Human liver microsomes pooled from 50 gender-balanced individuals. Gender-balanced pooling from 50 individuals

Specification

• Species: Human
• Source: Liver
• Description: The cytochrome P450 enzyme (CYP) family play a key role in hepatic elimination that occurs in the endoplasmic reticulum. Liver microsomes are the most convenient way to investigate CYP-mediated metabolism. Microsomes are a useful in vitro testing system as they contain all CYP enzymes and ensure the CYP kinetic measurements are not confused with other metabolic processes or cellular uptake. Microsomes are available from a range of species and suitable for a variety of experiments including metabolite characterization, Cytochrome P450 inhibition studies, and metabolic stability.
• Qualified for: CYP activity
• Applications: Microsomes are available from a range of species and suitable for a variety of experiments: Metabolite characterization Cytochrome P450 inhibition studies Metabolic stability
• Storage: Liquid nitrogen (stable for up to 12 months) Microsomes should be transferred to liquid nitrogen storage immediately upon receipt.
• Concentration: 10 mg protein/vial
• Handling: Microsomes should always be pipetted gently