Acetyl Histone H3-K9 Quantification Kit (Colorimetric) Kit-0020

September 27-30, 2022

Boston Convention and Exhibition Center

Booth #336

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Acetyl Histone H3-K9 Quantification Kit (Colorimetric)

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Home / Products / Assay Kits / Epigenetic Kits / Acetyl Histone H3-K9 Quantification Kit (Colorimetric)

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Cat.No. : Kit-0020 Optional Service: Optional requirements on this protein
Product Overview : Acetyl Histone H3-K9 Quantification Kit (Colorimetric) is use for measuring acetylation of histone H3-K9.
Description : Acetylation of histones including histone H3 has been involved in the regulation of chromatin structure and recruitment of transcription factors to the gene promoters. Histone acetyltransfeases (HAT) and histone deacetylases (HDACs) play a critical role in control of histone H3 acetylation at multiple sites. Histone H3 at lysine 9 (H3-K9) is a primary acetylated site of histone H3. Acetylation of histone H3-K9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Acetylation of histone H3-K9 is tightly involved in the cell cycle reguation, cell proliferation and apoptosis. Acetylation of histone H3-K9 is also an active marker and the balance between histone H3-K9 acetylation and methylation is important for the establishment of specific chromatin structures. An imbalance in the equilibrium of histone H3 acetylation including K9 acetylation has been associated with tumorigenesis and cancer progression. Histone H3-K9 acetylation may be increased by inhibition of HDACs and decreased by HAT inhibition. Thus quantitative detection of acetyl histone H3-K9 would provide useful information for better understanding epigenetic regulation of gene activation and for developing HAT or HDAC-targeted drugs. The Acetyl Histone H3-K9 Quantification Kit (Colorimetric) provides a tool for measuring acetylation of histone H3-K9.
Applications : For specifically measuring histone H3-K9 acetylation using a variety of mammalian cells (human, mouse, etc.) including fresh and frozen tissues, cultured adherent and suspension cells.
Storage : Upon receipt, store C3 and Standard control at –20°C. Store all other components at 4°C away from light. The components of the kit should be stable for 6 months when stored properly.Note: Check if buffers C1 and C2 contain salt precipitates before using. If so, warm (at room temperature or 37°C) and shake the buffers until the salts are redissolved.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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