Active Recombinant Full Length Human KIF11 Protein, C-Flag-tagged

• Cat.No.: KIF11-158HFL
• Product Overview: Recombinant Full Length Human KIF11 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Enzyme substrate
• Molecular Mass: 119 kDa
• AA Sequence: MASQPNSSAKKKEEKGKNIQVVVRC RPFNLAERKASAHSIVECDPVRKEV SVRTGGLADKSSRKTYTFDM VFGASTKQIDVYRSVVCPILDEVIM GYNCTIFAYGQTGTGKTFTMEGERS PNEEYTWEEDPLAGIIPRTL HQIFEKLTDNGTEFSVKVSLLEIYN EELFDLLNPSSDVSERLQMFDDPRN KRGVIIKGLEEITVHNKDEV YQILEKGAAKRTTAATLMNAYSSRS HSVFSVTIHMKETTIDGEELVKIGK LNLVDLAGSENIGRSGAVDK RAREAGNINQSLLTLGRVITALVER TPHVPYRESKLTRILQDSLGGRTRT SIIATISPASLNLEETLSTL EYAHRAKNILNKPEVNQKLTKKALI KEYTEEIERLKRDLAAAREKNGVYI SEENFRVMSGKLTVQEEQIV ELIEKIGAVEEELNRVTELFMDNKN ELDQCKSDLQNKTQELETTQKHLQE TKLQLVKEEYITSALESTEE KLHDAASKLLNTVEETTKDVSGLHS KLDRKKAVDQHNAEAQDIFGKNLNS LFNNMEELIKDGSSKQKAML EVHKTLFGNLLSSSVSALDTITTVA LGSLTSIPENVSTHVSQIFNMILKE QSLAAESKTVLQELINVLKT DLLSSLEMILSPTVVSILKINSQLK HIFKTSLTVADKIEDQKKELDGFLS ILCNNLHELQENTICSLVES QKQCGNLTEDLKTIKQTHSQELCKL MNLWTERFCALEEKCENIQKPLSSV QENIQQKSKDIVNKMTFHSQ KFCADSDGFSQELRNFNQEGTKLVE ESVKHSDKLNGNLEKISQETEQRCE SLNTRTVYFSEQWVSSLNER EQELHNLLEVVSQCCEASSSDITEK SDGRKAAHEKQHNIFLDQMTIDEDK LIAQNLELNETIKIGLTKLN CFLEQDLKLDIPTGTTPQRKSYLYP STLVRTEPREHLLDQLKRKQPELLM MLNCSENNKEETIPDVDVEE AVLGQYTEEPLSQEPSVDAGVDCSS IGGVPFFQHKKSHGKDKENRGINTL ERSKVEETTEHLVTKSRLPL
  RAQINLTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome

Gene Information

• Gene Name: KIF11 kinesin family member 11 [ Homo sapiens (human) ]
• Official Symbol: KIF11
• Synonyms: EG5; HKSP; KNSL1; MCLMR; TRIP5
• Gene ID: 3832
• mRNA Refseq: NM_004523.4
• Protein Refseq: NP_004514.2
• MIM: 148760
• UniProt ID: P52732