Active Recombinant Full Length Human SCG2 Protein, C-Flag-tagged

• Cat.No.: SCG2-485HFL
• Product Overview: Recombinant Full Length Human SCG2 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Cell treatment
• Molecular Mass: 70.8 kDa
• AA Sequence: MAEAKTHWLGAALSLIPLIFLISGA EAASFQRNQLLQKEPDLRLENVQKF PSPEMIRALEYIENLRQQAH KEESSPDYNPYQGVSVPLQQKENGD ESHLPERDSLSEEDWMRIILEALRQ AENEPQSAPKENKPYALNSE KNFPMDMSDDYETQQWPERKLKHMQ FPPMYEENSRDNPFKRTNEIVEEQY TPQSLATLESVFQELGKLTG PNNQKRERMDEEQKLYTDDEDDIYK ANNIAYEDVVGGEDWNPVEEKIESQ TQEEVRDSKENIEKNEQIND EMKRSGQLGIQEEGLRKESKDQLSD DVSKVIAYLKRLVNAAGSGRLQNGQ NGERATRLFEKPLDSQSIYQ LIEISRNLQIPPEDLIEMLKTGEKP NGSVEPERELDLPVDLDDISEADLD HPDLFQNRMLSKSGYPKTPG GAGTEALPDGLSVEDILNLLGMESA ANQKTSYFPNPYNQEKVLPRLPYGA GRSRSNQLPKAAWIPHVENR QMAYENLNDKDQELGEYLARMLVKY PEIINSNQVKRVPGQGSSEGDLQEE EQIEQAIKEHLNQGSSQETD
  KLAPVSKRFPVGPPKNDDTPNRQYW DEDLLMKVLEYLNQEKAEKGREHIA KRAMENMTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein, Transmembrane

Gene Information

• Gene Name: SCG2 secretogranin II [ Homo sapiens (human) ]
• Official Symbol: SCG2
• Synonyms: SN; CHGC; EM66; SgII
• Gene ID: 7857
• mRNA Refseq: NM_003469.5
• Protein Refseq: NP_003460.2
• MIM: 118930
• UniProt ID: P13521