Active Recombinant Full Length Human TRH Protein, C-Flag-tagged

• Cat.No.: TRH-368HFL
• Product Overview: Recombinant Full Length Human TRH Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Cell treatment
• Molecular Mass: 27.2 kDa
• AA Sequence: MPGPWLLLALALTLNLTGVPGGRAQ PEAAQQEAVTAAEHPGLDDFLRQVE RLLFLRENIQRLQGDQGEHS ASQIFQSDWLSKRQHPGKREEEEEE GVEEEEEEEGGAVGPHKRQHPGRRE DEASWSVDVTQHKRQHPGRR SPWLAYAVPKRQHPGRRLADPKAQR SWEEEEEEEEREEDLMPEKRQHPGK RALGGPCGPQGAYGQAGLLL
  GLLDDLSRSQGAEEKRQHPGRRAAW VREPLEETRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Secreted Protein

Gene Information

• Gene Name: TRH thyrotropin releasing hormone [ Homo sapiens (human) ]
• Official Symbol: TRH
• Synonyms: TRF; Pro-TRH
• Gene ID: 7200
• mRNA Refseq: NM_007117.5
• Protein Refseq: NP_009048.1
• MIM: 613879
• UniProt ID: P20396