Active Recombinant Human C5AR1 Protein, Myc/DD-tagged

• Cat.No.: C5AR1-02H
• Product Overview: Recombinant protein of human complement component 5a receptor 1 (C5AR1) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Bio-activity: Binding assay
• Molecular Mass: 39.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: C5AR1 complement C5a receptor 1 [ Homo sapiens (human) ]
• Official Symbol: C5AR1
• Synonyms: C5AR1; complement C5a receptor 1; C5A; C5AR; C5R1; CD88; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5a-R; complement component 5a receptor 1
• Gene ID: 728
• mRNA Refseq: NM_001736
• Protein Refseq: NP_001727
• MIM: 113995
• UniProt ID: P21730