Active Recombinant Human Calmodulin 1 (Phosphorylase Kinase, Delta)
Cat.No. : | CALM1-88H |
Product Overview : | Recombinant Human Calmodulin full length protein expressed inE.coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CALM1-88H |
Description : | Calmodulin (CaM) is an intracellular receptor protein for Ca2+-ions. It activates the myosin light chain kinase which is the catalyst of myosin phosphorylation. CaM participates in the activation of enzymes such as cyclic nucleotide- dependent phosphodiesterase, calcineurin, ATPase, Myosin Light Chain Kinases, and CAM kinase. |
Source : | Escherichia Coli. |
Physical Appearance : | Sterile Filtered clear solution. |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Formulation : | Calmodulin at 1mg/ml in 20mM HEPES-KOH, pH7, 50mM NaCl, 1mM EDTA and 1mM DTT. |
Activity : | Assayed for calcium binding and activation of MLCK. |
Applications : | • ELISA • Inhibition Assays • Western Blotting |
Storage : | Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles. |
Gene Name : | CALM1 calmodulin 1 (phosphorylase kinase, delta) [ Homo sapiens ] |
Synonyms : | CALM1; calmodulin 1 (phosphorylase kinase, delta); CAMI; PHKD; DD132; CALML2; calmodulin 1; phosphorylase kinase, delta subunit; EC 2.7.11.19; CALMCAM; CAM1; CAM2; CAM3; CAMB; CAMC; CAMIII; CaM |
Gene ID : | 801 |
mRNA Refseq : | NM_001166106 |
Protein Refseq : | NP_001159578 |
MIM : | 114180 |
UniProt ID : | P62158 |
Chromosome Location : | 14q24-q31 |
Pathway : | Alzheimer"s disease; Calcium signaling pathway; Glioma; GnRH signaling pathway; Insulin signaling pathway; Long-term potentiation; Melanogenesis; Neurotrophin signaling pathway; Olfactory transduction; Phosphatidylinositol signaling system; Vascular smooth muscle contraction |
Products Types
◆ Recombinant Protein | ||
CALM1-01H | Active Recombinant Human CALM1 Protein | +Inquiry |
CALM1-03H | Recombinant Human CALM1 Protein | +Inquiry |
CALM1-1189M | Recombinant Mouse CALM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CALM1-757R | Recombinant Rat CALM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CALM1-2586H | Recombinant Human CALM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CALM1-7890HCL | Recombinant Human CALM1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCALM1 plays a crucial role in mediating calcium-dependent signaling pathways, influencing processes such as muscle contraction, neurotransmitter release, and gene expression.
Techniques like co-immunoprecipitation and fluorescence resonance energy transfer (FRET) are used to study CALM1's interactions. This knowledge is crucial for drug development and disease research.
CALM1 is a small calcium-binding protein. It undergoes conformational changes upon binding calcium ions, allowing it to regulate various cellular processes.
CALM1 modulates neuronal excitability by regulating calcium channels and neurotransmitter release. It is crucial for normal neuronal function.
CALM1 binds to and activates various enzymes and proteins in response to changes in calcium levels, regulating diverse cellular functions and maintaining homeostasis.
Customer Reviews (3)
Write a reviewThe quality of the product is unmatched, and it's worth every penny.
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