| Cat.No. : |
CCL23-034H
Optional Service: Optional requirements on this protein
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| Product Overview : |
Purified recombinant protein of Human chemokine (C-C motif) ligand 23 (CCL23 / MPIF-1)(Arg46-Asn120), transcript variant CKbeta8, was expressed in E. coli. |
| Description : |
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]. |
| Source : |
E. coli |
| Species : |
Human |
| Bio-activity : |
Bioactivity was measured by its property to chemoattract THP-1 cells in a dose dependent manner. |
| Molecular Mass : |
8.5 kDa |
| Endotoxin : |
Less than 0.01 ng per µg protein as determined by the LAL method. |
| Purity : |
> 98% as determined by Coomassie stained SDS-PAGE. |
| Concentration : |
Protein formulated and vialed at >50 µg/mL in specified buffer |
| Storage Buffer : |
1 x PBS |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
