Active Recombinant Human CD93 protein, hFc-tagged

• Cat.No.: CD93-0309H
• Product Overview: Recombinant Human CD93 protein(Q9NPY3)(Met1-Lys580), fused with hFc tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: hFc
• Form: Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Bio-activity: Immobilized Human IGFBP7 (His Tag) at 2 μg/ml (100 μl/well) can bind Human CD93 (hFc Tag). The EC50 is 15-120 ng/ml.
• Molecular Mass: The recombinant human CD93/Fc is a disulfide-linked homodimer. The reduced monomer consists of 800 amino acids after removal the signal peptide and has a predicted molecular mass of 85.2 kDa. As a result of glycosylation, rh CD93/Fc monomer migrates as an approximately 125 kDa band in SDS-PAGE under reducing conditions.
• Proteinlength: Met1-Lys580
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 85 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: CD93 CD93 molecule [ Homo sapiens ]
• Official Symbol: CD93
• Synonyms: CD93; CD93 molecule; C1QR1, CD93 antigen , complement component 1, q subcomponent, receptor 1 , matrix remodelling associated 4 , MXRA4; complement component C1q receptor; C1qR(P); C1qRP; CDw93; dJ737E23.1; ECSM3; C1qR; CD93 antigen; C1q receptor 1; C1q/MBL/SPA receptor; matrix-remodelling associated 4; matrix-remodeling-associated protein 4; complement component 1 q subcomponent receptor 1; complement component 1, q subcomponent, receptor 1; C1QR1; MXRA4
• Gene ID: 22918
• mRNA Refseq: NM_012072
• Protein Refseq: NP_036204
• MIM: 120577
• UniProt ID: Q9NPY3