Active Recombinant Human CLEC9A Protein, Fc-tagged

• Cat.No.: CLEC9A-01H
• Product Overview: Recombinant Human CLEC10A (Lys57-Val241) Protein with a Human IgG1 tag (Pro100-Lys330) at N-terminus was expressed in Mouse myeloma cell line NS0 cell.

Specification

• Species: Human
• Source: Mouse myeloma cell
• Tag: Fc
• Protein Length: 57-241 a.a.
• Description: CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells.
• Form: Disulfide-linked homodimer
• Bio-activity: Measured by flow cytometry for its ability to bind a ligand expressed in FasL-treated mouse B cells. At 100 ng/mL, > 50% of necrotic cells bind to Recombinant Human CLEC9a.
• Molecular Mass: 47.8 kDa
• N-terminal Sequence Analysis: Met
• Endotoxin: <0.10 EU/μg of the protein by the LAL method.
• Purity: > 95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Applications: Bioactivity
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: CLEC9A C-type lectin domain containing 9A [ Homo sapiens (human) ]
• Official Symbol: CLEC9A
• Synonyms: CLEC9A; C-type lectin domain containing 9A; CD370; DNGR1; DNGR-1; UNQ9341; C-type lectin domain family 9 member A; HEEE9341
• Gene ID: 283420
• mRNA Refseq: NM_207345
• Protein Refseq: NP_997228
• MIM: 612252
• UniProt ID: Q6UXN8