Active Recombinant Human Defensin, Beta 1
Cat.No. : | DEFB1-035H |
Product Overview : | Recombinant human DEFB1 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | DEFB1-035H |
Description : | Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. |
Source : | Human |
Host : | E. coli |
Form : | Supplied as a lyophilized powder. |
Purity : | >98% pure by SDS PAGE and HPLC |
Sequence : | Region of BD1 protein corresponding to amino acids DHYNCVSSGG QCLYSACPIF TKIQGTCYRG KAKCCK. |
Molecular Mass : | 3.9 kDa |
Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
Bioactivity : | Determined by its ability to chemoattract CD34+ dendritic cells using a concentration range of 100.0-1000.0 ng/ml. |
Storage : | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | DEFB1 defensin, beta 1 [ Homo sapiens ] |
Official Symbol : | DEFB1 |
Synonyms : | DEFB1; BD1; DEFB101; HBD1; hBD-1; beta-defensin-1; defensin beta 1; MGC51822; Beta-defensin 1 precursor; BD-1; DEFB1 |
Gene ID : | 1672 |
mRNA Refseq : | NM_005218 |
Protein Refseq : | NP_005209 |
MIM : | 602056 |
UniProt ID : | P60022 |
Chromosome Location : | 8p23.1 |
Products Types
◆ Recombinant Protein | ||
DEFB1-455H | Recombinant Human DEFB1 Protein, MYC/DDK-tagged | +Inquiry |
DEFB1-2705P | Recombinant Pig DEFB1 Protein, His-tagged | +Inquiry |
DEFB1-1052R | Recombinant Rhesus Macaque DEFB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
DEFB1-134D | Active Recombinant Human DEFB1 Protein (47 aa) | +Inquiry |
DEFB1-2300M | Recombinant Mouse DEFB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DEFB1-6989HCL | Recombinant Human DEFB1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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