Active Recombinant Human HEXA protein, His-tagged

• Cat.No.: HEXA-2523H
• Product Overview: Recombinant Human HEXA protein(Met1-Thr529)(AAD13932.1), fused with His tag, was expressed in Insect Cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: Met1-Thr529
• Form: Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Bio-activity: Measured by its ability to hydrolyze 4-methylumbelliferyl-N-acetyl-β-D-glucosaminide (4-MU-Glc-NAc).The specific activity is >1,250 pmoles/min/μg.
• Molecular Mass: The recombinant human HEXA consists of 517 amino acids and predicts a molecular mass of 59.7 kDa. It migrates as an approximately 64 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: HEXA hexosaminidase A (alpha polypeptide) [ Homo sapiens ]
• Official Symbol: HEXA
• Synonyms: HEXA; hexosaminidase A (alpha polypeptide); beta-hexosaminidase subunit alpha; GM2 gangliosidosis; Tay Sachs disease; hexosaminidase subunit A; beta-N-acetylhexosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit alpha; TSD; MGC99608
• Gene ID: 3073
• mRNA Refseq: NM_000520
• Protein Refseq: NP_000511
• MIM: 606869
• UniProt ID: P06865