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Active Recombinant Human IL17RA&IL17RC protein, Fc-tagged

Cat.No. : IL17RA&IL17RC-1628H
Product Overview : Recombinant Human IL17RA&IL17RC protein(Leu33-Trp320(IL-17RA)&Leu21-His465(IL-17RC)), fused with Fc tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Bio-activity : Immobilized Human IL-17A&IL-17F Heterodimer Protein, His Tag&Strep II Tag at 2 μg/mL (100 μL/well) can bind Human IL17RA&IL17RC Protein, Fc Tag&Fc Tag with a linear range of 1-20 ng/mL.Immobilized Human IL17A, Tag Free at 2 μg/mL (100 μL/well) can bind Human IL17RA&IL17RC Protein, Fc Tag&Fc Tag with a linear range of 0.6-10 ng/mL.Immobilized Human IL-17F (H161R), His Tag at 2 μg/mL (100 μL/well) can bind Human IL17RA&IL17RC Protein, Fc Tag&Fc Tag with a linear range of 1-39 ng/mL.
Molecular Mass : Human IL17RA&IL17RC Protein, Fc Tag&Fc Tag is produced by co-expression of IL-17RA and IL-17RC, has a calculated MW of 60.0 kDa (IL-17RA) & 75.7 kDa (IL-17RC). Subunit IL-17RA is fused with a human IgG1 Fc tag at the C-terminus and subunit IL-17RC is fused with a human IgG1 Fc tag at the C-terminus. The reducing (R) heterodimer protein migrates as 80-90 kDa and 100-110 kDa due to glycosylation.
Proteinlength : Leu33-Trp320(IL-17RA)&Leu21-His465(IL-17RC)
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Storage : For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at:
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : IL17RA interleukin 17 receptor A [ Homo sapiens ]
Official Symbol : IL17RA
Synonyms : IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262;
Gene ID : 23765
mRNA Refseq : NM_014339
Protein Refseq : NP_055154
MIM : 605461
UniProt ID : Q96F46

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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