Active Recombinant Human KYNU Protein, His-tagged

• Cat.No.: KYNU-541H
• Product Overview: Recombinant Human KYNU (Accession # NP_003928) Met1-Asn465, fused with a C-terminal 10-His tag, was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived.

Specification

• Species: Human
• Source: Sf21 Cells
• Tag: His
• Protein Length: Met1-Asn465
• Predicted N Terminal: Met1
• Form: Supplied as a 0.2 µm filtered solution in MES and NaCl.
• Bio-activity: Measured by its ability to oxidize 3-hydroxy kynurenine. The specific activity is >75 pmol/min/µg, as measured under the described conditions.
• Molecular Mass: Recombinant Human KYNU, His-tagged has a calculated MW of 54 kDa. In SDS-PAGE migrates as 51 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: KYNU kynureninase [ Homo sapiens ]
• Official Symbol: KYNU
• Synonyms: KYNU; kynureninase; kynureninase (L kynurenine hydrolase); L kynurenine hydrolase; kynureninase (L-kynurenine hydrolase)
• Gene ID: 8942
• mRNA Refseq: NM_001032998
• Protein Refseq: NP_001028170
• MIM: 605197
• UniProt ID: Q16719
• Chromosome Location: 2q22.2