Active Recombinant Human Leucine Rich Repeat Transmembrane Neuronal 3, His-tagged
| Cat.No. : | LRRTM3-5683H |
| Product Overview : | Recombinant Human LRRTM3protein was expressed in Murine myeloma cell line with a C-terminal 6-Histag. Glu31-Lys419. |
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| Species : | Human |
| Source : | Mammalian Cells |
| Tag : | His |
| Protein Length : | 31-419 a.a. |
| Description : | Human LRRTM3 is a 63kDa type I transmembrane protein, and one of four members of the LRRTM familyof proteins within the leucine-rich repeat superfamily. There are twoisoforms of LRRTM3. Isoform 1 is synthesized as a precursor with a 30 aminoacid signal sequence, a 389 aa extracellular region, a 21 aa transmembraneregion, and a 141 aa cytoplasmic region. In isoform 2, aa 513 is changed fromisoleucine to valine, and aa 514 to 581 are missing, producing a cytoplasmicregion of only 74 aa. |
| Form : | Lyophilized from a0.2 μm filtered solution in PBS. |
| N-terminalSequence : | Glu31 |
| Molecular Weight : | 45.2 kDa |
| Activity : | Measuredby its ability to enhance neurite outgrowth of E16-E18 rat embryonic corticalneurons. Able to significantly enhance neurite outgrowth when immobilized asa 3 μL droplet containing 60-250 ng on a nitrocellulose-coated microplate. |
| Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
| SDS-PAGE : | 50-60kDa, reducing conditions. |
| Purity : | >90%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Reconstitution : | 100μg/mL in sterile PBS |
| Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterileconditions after reconstitution. |
| Gene Name | LRRTM3 leucine rich repeattransmembrane neuronal 3 [ Homo sapiens ] |
| Official Symbol | LRRTM3 |
| Synonyms | LRRTM3; leucine richrepeat transmembrane neuronal 3; MGC131810; leucine-rich repeat transmembraneneuronal protein 3; UNQ803/PRO1693; OTTHUMP00000019682; OTTHUMP00000019683 |
| Gene ID | 347731 |
| mRNA Refseq | NM_178011 |
| Protein Refseq | NP_821079 |
| MIM | 610869 |
| UniProt ID | Q86VH5 |
| Chromosome Location | 10q22.1 |
Not For Human Consumption!
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