Active Recombinant Human LOX Protein, Myc/DDK-tagged

• Cat.No.: LOX-91H
• Product Overview: Recombinant protein of human lysyl oxidase (LOX) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Protein Length: 1-417 aa
• Description: This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
• Bio-activity: Enzyme activity; In vivo treatment; Cell treatment; Binding assay; In vivo treatment
• Molecular Mass: 46.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: > 50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: LOX lysyl oxidase [ Homo sapiens (human) ]
• Official Symbol: LOX
• Synonyms: LOX; lysyl oxidase; AAT10; protein-lysine 6-oxidase; EC 1.4.3.13
• Gene ID: 4015
• mRNA Refseq: NM_002317
• Protein Refseq: NP_002308
• MIM: 153455
• UniProt ID: P28300