Active Recombinant Human PTPRC, His-tagged
Cat.No. : | PTPRC-1522H |
Product Overview : | Recombinant human PTPRC (604-end) was expressed in Sf9 insect cells using an N-terminal His tag. |
- Specification
- Gene Information
- Related Products
Description : | PTPRC (CD45) contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. PTPRC has been shown to be an essential regulator of T- and B-cell antigen receptor signaling.It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | His |
Form : | Recombinant protein stored in 50mM MOPS, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
Bio-activity : | 11,500 nmol/min/mg |
Molecular Mass : | ~95 kDa |
Protein length : | 604 aa-end |
Purity : | >90% |
Applications : | Phosphatase Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PTPRC protein tyrosine phosphatase, receptor type, C [ Homo sapiens ] |
Official Symbol : | PTPRC |
Synonyms : | PTPRC; protein tyrosine phosphatase, receptor type, C; CD45; receptor-type tyrosine-protein phosphatase C; GP180; LCA; T200; CD45 antigen; T200 glycoprotein; leukocyte common antigen; leukocyte-common antigen; T200 leukocyte common antigen; protein tyrosine phosphatase, receptor type, c polypeptide; LY5; B220; L-CA; CD45R; |
Gene ID : | 5788 |
mRNA Refseq : | NM_002838 |
Protein Refseq : | NP_002829 |
MIM : | 151460 |
UniProt ID : | P08575 |
Chromosome Location : | 1q31-q32 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; |
Function : | hydrolase activity; protein binding; protein kinase binding; protein tyrosine phosphatase activity; receptor activity; transmembrane receptor protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
PTPRC-730H | Recombinant Human PTPRC Protein, His-tagged | +Inquiry |
PTPRC-1262H | Acitve Recombinant Human PTPRC protein(Met1-Lys416), hFc-tagged | +Inquiry |
PTPRC-133H | Active Recombinant Human PTPRC Protein, His-tagged | +Inquiry |
PTPRC-4497R | Recombinant Rat PTPRC Protein, His (Fc)-Avi-tagged | +Inquiry |
Ptprc-550M | Active Recombinant Mouse Ptprc protein(Arg453-Ser1152) | +Inquiry |
◆ Lysates | ||
PTPRC-1141MCL | Recombinant Mouse PTPRC cell lysate | +Inquiry |
PTPRC-3045HCL | Recombinant Human PTPRC cell lysate | +Inquiry |
PTPRC-001MCL | Recombinant Mouse PTPRC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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