Active Recombinant Human RIPK4 Protein, GST&His tagged

• Cat.No.: RIPK4-01H
• Product Overview: Human RIPK4, N-terminal fragment, amino acids M1-D300 (as in NCBI/Protein entry NP_065690.2), N-terminal GST&His×6 fusion protein with a 3C cleavage site, expressed in Sf9 insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST&His
• Protein Length: 1-300 aa
• Description: The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
• Form: 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 15 mM reduced glutathione, 20% glycerol.
• Bio-activity: Specific kinase activity (Pi transfer): 2 pmol/μg×min ATP-KM: 0.17 μM
• Molecular Mass: 63, 283 Da
• AASequence: GDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFKDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHPPKSDPMGGRDSPLAMGARGRMEGDGGTPWALALLRTFDAGEFTGWEKVGSGGFGQVYKVRHVHWKTWLAIKHHHHHHLEVLFQGCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICREPVGLVMEYMETGSLEKLLASEPLPWDLRFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAKCNGLSHSHDLSMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDLCEKPDDEVKETAHD
• Storage: At -80 centigrade. For complete recovery, mix well and spin before use. Product must not be stored in diluted solutions, aliquots below 10 μL are not advisable. Avoid repeated freeze-thaw cycles!
• Concentration: 0.319 μg/μL

Gene Information

• Gene Name: RIPK4 receptor-interacting serine-threonine kinase 4 [ Homo sapiens (human) ]
• Official Symbol: RIPK4
• Synonyms: RIPK4; receptor-interacting serine-threonine kinase 4; ANKRD3, ankyrin repeat domain 3; receptor-interacting serine/threonine-protein kinase 4; ANKK2; DIK; PKC delta interacting protein kinase; PKK; protein kinase C associated kinase; RIP4; protein kinase C-associated kinase; PKC-delta-interacting protein kinase; serine/threonine-protein kinase ANKRD3; ankyrin repeat domain-containing protein 3; NKRD3; ANKRD3; MGC129992; MGC129993
• Gene ID: 54101
• mRNA Refseq: NM_020639
• Protein Refseq: NP_065690
• MIM: 605706
• UniProt ID: P57078