Active Recombinant Human ROS1 Protein, G2032R, L2086F, GST tagged

• Cat.No.: ROS1-15H
• Product Overview: Human ROS, cytoplasmic domain [1883-2347(end) amino acids and G2032R/L2086F of accession number NP_002935.2] was expressed as N-terminal GST-fusion protein (79 kDa) using baculovirus expression system. GST-ROS[G2032R/L2086F] was purified by using glutathione sepharose chromatography.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Protein Length: 1883-2347 aa
• Description: This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 79 kDa
• Storage: Store at -80 centigrade. Avoid repeating freeze-thaws.

Gene Information

• Gene Name: ROS1 c-ros oncogene 1, receptor tyrosine kinase [ Homo sapiens (human) ]
• Official Symbol: ROS1
• Synonyms: ROS1; c-ros oncogene 1, receptor tyrosine kinase; v ros avian UR2 sarcoma virus oncogene homolog 1, v ros UR2 sarcoma virus oncogene homolog 1 (avian); proto-oncogene tyrosine-protein kinase ROS; c ros 1; MCF3; ROS; proto-oncogene c-Ros; proto-oncogene c-Ros-1; c-Ros receptor tyrosine kinase; receptor tyrosine kinase c-ros oncogene 1; v-ros UR2 sarcoma virus oncogene homolog 1; transmembrane tyrosine-specific protein kinase; v-ros avian UR2 sarcoma virus oncogene homolog 1; c-ros-1
• Gene ID: 6098
• mRNA Refseq: NM_002944
• Protein Refseq: NP_002935
• MIM: 165020
• UniProt ID: P08922