Active Recombinant Human SENP2 protein, His-tagged

• Cat.No.: SENP2-152H
• Product Overview: Recombinant Human SENP2 fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.
• Form: 50 mM HEPES, pH 7.5, 150 mM NaCl, 10% glycerol
• Bio-activity: ≥10^5 Units/mg
• Molecular Mass: 28 kDa
• Purity: ≥95% by SDS-PAGE and RP-HPLC
• Unit Definition: 1 Unit of SUMO Protease 2 cleaves >90% of 100 µg SUMO Protease 2 Control Protein in 1 hour (37 centigrade)
• Applications: Useful for removal of SUMO-tags from recombinant SUMO fusion proteins
• Storage: Store at or below –80 centigrade. Stable as supplied for up to 1 year when stored dessicated at –80 centigrade. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 [ Homo sapiens ]
• Official Symbol: SENP2
• Synonyms: SENP2; SUMO1/sentrin/SMT3 specific peptidase 2; SUMO1/sentrin/SMT3 specific protease 2; sentrin-specific protease 2; AXAM2; DKFZp762A2316; KIAA1331; SMT3IP2; SMT3-specific isopeptidase 2; sentrin/SUMO-specific protease SENP2
• Gene ID: 59343
• mRNA Refseq: NM_021627
• Protein Refseq: NP_067640
• MIM: 608261
• UniProt ID: Q9HC62
• Chromosome Location: 3q28
• Pathway: Nuclear pore complex, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem
• Function: SUMO-specific protease activity; cysteine-type peptidase activity; peptidase activity; protein binding; protein domain specific binding