Active Recombinant human TNFAIP3 protein, C-His and N-DDDDK tagged
Cat.No. : | TNFAIP3-25H |
Product Overview : | Recombinant Active Human TNFAIP3 Protein (Full length, 2 to 790) with C-His and N-DDDDK tag was expressed in Baculovirus infected Sf9 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. |
Source : | Baculovirus infected Sf9 cells |
Species : | Human |
Tag : | C-His and N-DDDDK |
Form : | Liquid |
Bio-activity : | Specific activity: 0.766 pmol/min/μg Assay Conditions: Reaction was performed in 50 mM Tris pH 7.4, 1 mM DTT, 0.5 mM EDTA, 500 nM Ub-AMC, and various amount of TNFAIP3 in a volume of 50 μL. Reaction was incubated at 37 centigrade for 30 min and fluorescent signal was measured at excitation of 360 nm, and emission at 460 nm. |
Molecular Mass : | 91 kDa including tags |
Protein Length : | Full length, 2 to 790 |
Purity : | 79% SDS-PAGE |
Applications : | SDS-PAGE; Functional Studies |
Storage : | Store at -80 centigrade. Avoid freeze/thaw cycle. This product is an active protein and may elicit a biological response in vivo, handle with caution. |
Storage Buffer : | pH: 8.00 Constituents: 0.63% Tris HCl, 64% Sodium chloride, 0.017% Potassium chloride, 0.04% Tween, 0.05% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 20% Glycerol (glycerin, glycerine) |
Shipping : | Shipped on Dry Ice |
Gene Name : | TNFAIP3 TNF alpha induced protein 3 [ Homo sapiens (human) ] |
Official Symbol : | TNFAIP3 |
Synonyms : | TNFAIP3; TNF alpha induced protein 3; A20; AISBL; AIFBL1; OTUD7C; TNFA1P2; tumor necrosis factor alpha-induced protein 3; OTU domain-containing protein 7C; putative DNA-binding protein A20; tumor necrosis factor inducible protein A20; tumor necrosis factor, alpha induced protein 3; zinc finger protein A20; EC 3.4.19.12 |
Gene ID : | 7128 |
mRNA Refseq : | NM_006290 |
Protein Refseq : | NP_006281 |
MIM : | 191163 |
UniProt ID : | P21580 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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