Active Recombinant Human TNFRSF17 Protein, Fc-tagged, FITC conjugated
Cat.No. : | TNFRSF17-1817HF |
Product Overview : | FITC conjugated human BCMA, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54 (Accession # NP_001183.2). |
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Description : | Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Bio-activity : | Immobilized Human BCMA, Fc Tag at 10 μg/mL (100 μL/well) can bind FITC-Labeled Human BAFF, Fc Tag with a linear range of 0.31-1.25 μg/mL. |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32 kDa. As a result of glycosylation, The protein migrates as 35-40 kDa under reducing (R) condition and 66 kDa under non-reducing (NR) condition on SDS-PAGE gel. |
Protein length : | Met1-Ala54 |
N-terminal Sequence Analysis : | Met 1 |
Endotoxin : | < 1.0 EU/ μg by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at: 4-8 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH7.5, 10% trehalose. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | TNFRSF17 TNF receptor superfamily member 17 [ Homo sapiens (human) ] |
Official Symbol : | TNFRSF17 |
Synonyms : | BCM; BCMA; CD269; TNFRSF13A; B cell maturation antigen; B-cell maturation factor; B-cell maturation protein |
Gene ID : | 608 |
mRNA Refseq : | NM_001192 |
Protein Refseq : | NP_001183 |
UniProt ID : | Q02223 |
Products Types
◆ Recombinant Protein | ||
TNFRSF17-321H | Active Recombinant Human TNFRSF17 Protein, MIgG2a Fc-tagged, low endotoxin | +Inquiry |
TNFRSF17-03H | Active Recombinant Human TNFRSF17 Protein, Fc-tagged, Atto 488 conjugated | +Inquiry |
TNFRSF17-101H | Recombinant Human TNFRSF17 Protein, His-tagged | +Inquiry |
TNFRSF17-100R | Recombinant Rhesus macaque TNFRSF17 Protein, Fc-tagged | +Inquiry |
TNFRSF17-240H | Active Recombinant Human TNFRSF17 Protein, His-Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
TNFRSF17-2489HCL | Recombinant Human TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-1489RCL | Recombinant Rat TNFRSF17 cell lysate | +Inquiry |
TNFRSF17-1253CCL | Recombinant Cynomolgus TNFRSF17 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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