Active Recombinant Human TNFSF9 Protein (Arg71-Glu254), C-His tagged, Animal-free, Carrier-free
Cat.No. : | TNFSF9-307H |
Product Overview : | Recombinant Human TNFSF9 Protein (Arg71-Glu254) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | 4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation. Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is 1-5 ng/mL. |
Molecular Mass : | The protein has a calculated MW of 20.4 kDa. The protein migrates as 20 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Arg71-Glu254 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >95% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 [ Homo sapiens (human) ] |
Official Symbol : | TNFSF9 |
Synonyms : | TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9; 4 1BB L; homolog of mouse 4 1BB L; receptor 4 1BB ligand; 4-1BBL; 4-1BB ligand; receptor 4-1BB ligand; homolog of mouse 4-1BB-L; CD137L; 4-1BB-L; |
Gene ID : | 8744 |
mRNA Refseq : | NM_003811 |
Protein Refseq : | NP_003802 |
MIM : | 606182 |
UniProt ID : | P41273 |
Products Types
◆ Recombinant Protein | ||
TNFSF9-585M | Recombinant Mouse TNFSF9 Protein, Fc-tagged | +Inquiry |
TNFSF9-231H | Active Recombinant Human TNFSF9 Protein (Leu 24 - Gln 186), His-tagged | +Inquiry |
TNFSF9-2019H | Recombinant Human TNFSF9 Protein, His-tagged | +Inquiry |
TNFSF9-1013R | Recombinant Rhesus TNFSF9 Protein (Arg128-Glu311), HlgG1 Fc-tagged | +Inquiry |
Tnfsf9-88M | Active Recombinant Mouse Tnfsf9 Protein (Arg104-Glu309), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
TNFSF9-2810MCL | Recombinant Mouse TNFSF9 cell lysate | +Inquiry |
TNFSF9-1445RCL | Recombinant Rat TNFSF9 cell lysate | +Inquiry |
TNFSF9-1444RCL | Recombinant Rat TNFSF9 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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