Active Recombinant Human TSPAN8 Full Length Transmembrane protein(Nanodisc)
Cat.No. : | TSPAN8-917H |
Product Overview : | Recombinant Human TSPAN8 Full Length Transmembrane protein(P19075), was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | N/A |
Form : | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Bio-activity : | Elisa plates were pre-coated with Flag Tag TSPAN8-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with TSPAN8-Nanodisc is 8.908ng/ml. |
Molecular Mass : | The human full length TSPAN8 protein has a MW of 26.0 kDa. |
Storage : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TSPAN8 tetraspanin 8 [ Homo sapiens ] |
Official Symbol : | TSPAN8 |
Synonyms : | TSPAN8; tetraspanin 8; TM4SF3, transmembrane 4 superfamily member 3; tetraspanin-8; CO 029; tspan-8; tumor-associated antigen CO-029; transmembrane 4 superfamily member 3; CO-029; TM4SF3; |
Gene ID : | 7103 |
mRNA Refseq : | NM_004616 |
Protein Refseq : | NP_004607 |
MIM : | 600769 |
UniProt ID : | P19075 |
Products Types
◆ Recombinant Protein | ||
TSPAN8-9689M | Recombinant Mouse TSPAN8 Protein, His (Fc)-Avi-tagged | +Inquiry |
TSPAN8-3251H | Recombinant Human TSPAN8 protein(Lys110-Asn205), mFc-tagged | +Inquiry |
TSPAN8-0747C | Recombinant Cynomolgus TSPAN8 protein, His-tagged | +Inquiry |
TSPAN8-321H | Recombinant Human TSPAN8, Fc tagged | +Inquiry |
TSPAN8-17517M | Recombinant Mouse TSPAN8 Protein | +Inquiry |
◆ Lysates | ||
TSPAN8-1064HCL | Recombinant Human TSPAN8 cell lysate | +Inquiry |
TSPAN8-997HCL | Recombinant Human TSPAN8 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionDetecting the expression level of TSPAN8 protein can help with the diagnosis and prognosis of certain diseases. For example, in colon cancer patients, high expression of the TSPAN8 protein is often associated with malignancy and poor prognosis of the tumor.
The interaction of the TSPAN8 protein with other proteins plays an important role in a variety of diseases. For example, in colon cancer, the TSPAN8 protein can interact with integrins, promoting the proliferation and migration of tumor cells. Therefore, understanding these interactions is important for understanding the pathogenesis of disease and the selection of therapeutic targets.
With the in-depth understanding of the structure and function of TSPAN8 protein, the drug development and application of TSPAN8 protein will be more extensive in the future. For example, the development of drugs targeting the TSPAN8 protein may be used to treat tumors, autoimmune diseases, and neurological diseases.
There are a variety of polymorphisms in the TSPAN8 gene that may affect the structure and function of proteins and are associated with the development of certain diseases. For example, one study found that a polymorphism in the TSPAN8 gene was associated with susceptibility to esophageal cancer in northern Chinese populations.
Studies have shown that the TSPAN8 protein can participate in the apoptosis process. It can regulate the permeability of mitochondrial membranes by interacting with members of the Bcl-2 family, thereby influencing the conduction of apoptosis signals.
The activity of TSPAN8 protein is affected by a variety of regulators, including phosphorylation modification, ubiquitination modification, etc. These regulators can influence the structure and function of the TSPAN8 protein and thus its biological function.
Customer Reviews (3)
Write a reviewDue to wide range of applications of TSPAN8 is impressive, and no matter what field, it can play an important role.
Band position of TSPAN8 in Western blot was consistent with the expected, showing good target recognition ability.
The stability of TSPAN8 is excellent, and its performance remains stable after many repeated uses, showing good product quality.
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