Active Recombinant Mouse CAMK1, GST-tagged

Cat.No. : CAMK1-1372M
Product Overview : Recombinant full-length mouse CAMK1 was expressed in E. coli cells using an N-terminal GST tag.
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Description : CAMK1 is a serine/threonine protein kinase that is a member of the multifunctional calcium/calmodulin-dependent protein kinase family. CAMK1 is ubiquitously expressed and phosphorylates a number of proteins including SYN1, SYN2, CREB and CFTR. In addition, Numb family of proteins may also be intracellular targets for CAMK1, and they may also be regulated by phosphorylation-dependent interaction with 14-3-3 protein. CAMK1 also plays an important role in the trafficking of HDAC7 between the cytoplasm and the nucleus. CAMK1 phosphorylates HDAC7 on multiple sites that lead to alteration in localization of HDAC7.
Source : E. coli
Species : Mouse
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Bio-activity : 3214 nmol/min/mg
Molecular Mass : ~70 kDa
Protein length : Full length
Purity : >90%
Applications : Kinase Assay, Western Blot
Storage : Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
Concentration : 0.1 μg/μl
Gene Name : Camk1 calcium/calmodulin-dependent protein kinase I [ Mus musculus ]
Official Symbol : CAMK1
Synonyms : CAMK1; calcium/calmodulin-dependent protein kinase I; calcium/calmodulin-dependent protein kinase type 1; caM-KI; caMKI-alpha; caM kinase I alpha; AI505105; CaMKIalpha; D6Ertd263e;
Gene ID : 52163
mRNA Refseq : NM_133926
Protein Refseq : NP_598687
Pathway : Calcium Regulation in the Cardiac Cell, organism-specific biosystem;
Function : ATP binding; calmodulin binding; calmodulin-dependent protein kinase activity; catalytic activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups;

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