Active Recombinant Mouse CD19 Protein, His-tagged

• Cat.No.: CD19-59M
• Product Overview: CD19 protein dimer contains a CD19 extracellular domain (UniProt# P25918) fused with a dimer motif followed by a His tag at the C-terminus.

Specification

• Species: Mouse
• Source: HEK293T
• Tag: His
• Protein Length: 19-287 aa
• Description: Mouse Cluster of Differentiation 19 (CD19) is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. CD19 is also known as B-Lymphocyte Surface Antigen B4, CVID3, B-lymphocyte antigen CD19, and T-Cell Surface Antigen Leu-12. CD19 is expressed on B cells throughout B cell development, but lost in plasma cells, and is also expressed on follicular dendritic cells. CD19 contains two extracellular C2-set Immunoglobulin-like (Ig-like) domains and a cytoplasmic tail that is highly conserved among mammalian species. CD19 can form multimolecular complexes with CD21 and CD81, but forming these complexes is not required for CD19 signal transduction. Mutations on CD19 are associated with severe immunodeficiency syndromes. CD19 is highly expressed on B cell cancers such as B cell lymphomas, acute lymphoblastic leukemia, and chronic lymphocytic leukemia.
• Molecular Mass: 75 kDa
• Homodimer/Heterodimer: Homodimer
• Purity: Greater than 90% dimer form as determined by SDS-PAGE under non-reducing condition
• Application: Verified Applications: ELISA for CD19-specific antibody binding assays. Suggested Applications: SPR & BLI for CD19 -specific antibody binding assays. Animal immunization, RUO.
• Storage: At -80 centigrade
• Storage Buffer: 0.22μm filtered PBS, pH 7.4
• Shipping: Frozen Dry Ice

Gene Information

• Gene ID: 12478
• Gene Name: Cd19 CD19 antigen [ Mus musculus (house mouse) ]
• Official Symbol: Cd19
• Synonyms: CD19; CD19 antigen; B-lymphocyte antigen CD19; differentiation antigen CD19; AW495831
• mRNA Refseq: NM_009844
• Protein Refseq: NP_033974
• UniProt ID: P25918