Active Recombinant Mouse Dipeptidylpeptidase 7, His-tagged Dpp7-416M

Active Recombinant Mouse Dipeptidylpeptidase 7, His-tagged


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Active Recombinant Mouse Dipeptidylpeptidase 7, His-tagged

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Cat.No. : Dpp7-416M Optional Service: Optional requirements on this protein
Product Overview : Recombinantmouse Dpp7 protein was expressed in Murine myeloma cell line, NS0-derived, with a C-terminal10-His tag.Asp34-Arg506
Description : The protein encodedby this gene is a post-proline cleaving aminopeptidase expressed in quiescentlymphocytes. The resting lymphocytes are maintained through suppression ofapoptosis, a state which is disrupted by inhibition of this novel serineprotease. The enzyme has strong sequence homology with prolylcarboxypeptidaseand is active at both acidic and neutral pH.
Source : Mammalian cells
Form : Lyophilized from a0.2 μm filtered solution in Tris and Nacl.
N-terminal Sequence : Asp34
Molecular Weight : 54 kDa
Activity : Measured by itsability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin(GP-AMC). The specific activity is > 2,500 pmoles/min/μg, as measuredunder the described conditions. See Activity Assay Protocol.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 200μg/mL in 25 mM Tris and 150 mM NaCl, pH 7.5.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3months, -20 to -70 °C under sterile conditions after reconstitution.
Rendering based onPDB 3JYH. :

Gene Name : Dpp7dipeptidylpeptidase 7 [ Mus musculus ]
Official Symbol : Dpp7
Synonyms : Dpp7;dipeptidylpeptidase 7; QPP; Dpp2; DPPII; OTTMUSP00000012875; dipeptidylpeptidase 2; dipeptidyl-peptidase 2; dipeptidyl peptidase II; dipeptidyl-peptidaseII; dipeptidyl aminopeptidase II; quiescent cell proline dipeptidase;Ec; dipeptidylpeptidase 7
Gene ID : 83768
mRNA Refseq : NM_031843
Protein Refseq : NP_114031
UniProt ID : Q9ET22
Chromosome Location : 2
Function : aminopeptidase activity;dipeptidyl-peptidase activity; hydrolase activity; peptidase activity;serine-type peptidase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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